Protein Alignment Ace and cest-8

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 149/621 - (23%)
• Similarity: 248/621 - (39%)
• Gaps: 171/621 - (27%)

  Fly    25 LVLVLSLHLSGVCGVIDRL----VVQTSSGPVRGRSVTVQGREVHVYT--GIPYAKPPVEDLRFR 83
            ||.:|.|     |.::...    ::.||.|.:||.:....... |.:|  .:|:||||:.:|||.
 Worm     2 LVSILLL-----CSLLYEFQTLKIINTSYGKLRGMAEWSDDAN-HKFTFKSVPFAKPPIGNLRFA 60

  Fly    84 KPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGR 148
            .|...:.|.|:|||:..||.|:           ........:.|:|||||||::...|.
 Worm    61 PPQKLDHWDGILDASVYSAACM-----------SNSTLTTQSYVNEDCLYINIFTSEKC------ 108

  Fly   149 GANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSAT-------LDIY-NADIM 205
                                      ..:...::::.:||.:.|.|||       ||.| :.|::
 Worm   109 --------------------------LKSKCSVIVYFHGGAYNTESATMFSDRFILDRYVHEDVI 147

  Fly   206 AAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWM 270
            ..:..|       |:|.||.|:..   |:.:..|   |:.::|..||:.::.:....|||:||.:
 Worm   148 FVIPAV-------RLGVFGQLYFG---PNAYLTE---NLFMFDAILALDFVHNEISNFGGDPEKV 199

  Fly   271 TLFGESAGSSSVNA----QLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNC- 330
            |:.|.|:|.:.|.|    .::.|..: |.::.:|.|.|....:..:..:.:..|    :....|
 Worm   200 TIMGHSSGGTLVEALGFSSMVDPELK-LFQQMIMLSSTGMFGFDDLVIDNSFTI----VEKLGCF 259

  Fly   331 NASMLKTNPAHV---MSCMRSVDA-KTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLM--KT 389
            |.:..:.|..:|   :.|||.:|. :.:.|||.......|||.       ..|...|..|:  ..
 Worm   260 NGTKEERNTVNVAETLDCMRHIDGYEILRVQQKMELMDQLSFK-------YLLRGAPFMLLNGNI 317

  Fly   390 ADLK----DYDILMGNVRDEGTYF-----LLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQA 445
            ||||    ..:.:.|....|  :|     .||..:.:.|.::..|:.|:....:|.|:....|
 Worm   318 ADLKKNTSPRNAIFGTTEHE--FFDVTEKYLYITVTFLDYENPVAVARNYDGRLMKNMETMIT-- 378

  Fly   446 EREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLW 510
            ...|.||..|:                      ||     |.|:|..||.|  :.|..|.|.|
 Worm   379 GDSAAIFVSTA----------------------TC-----AAAMANAGADV--FLFETRQSYS-- 412

  Fly   511 GEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVI-EFAKTGNPAQDGEEWPNFSKED 574
                  :|..:::||.|   |:....|.::.::.....|.:: .|.|.|.|:      |.:...|
 Worm   413 ------VHVSDMQYFIG---NHCAHNRTIDIDILDSFYSKLLTNFTKHGKPS------PGWDPVD 462

  Fly   575 P--VYYIFSTDDKIEKLAR-GPL------AARCSFW 601
            |  :.|:   :.|::..|| ||:      |...|||
 Worm   463 PGRMNYL---ELKVDSKARSGPVMLEGYHAKDVSFW 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	142/603 (24%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	142/597 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910