Protein Alignment Ace and cest-13

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 673
• Identity: 146/673 - (21%)
• Similarity: 227/673 - (33%)
• Gaps: 206/673 - (30%)

  Fly    23 LPLVLVLSLHLSGVCG--VIDRLVVQTSSGPVRGRSVTVQGREVHVY----TGIPYAKPPVEDLR 81
            |.:..:|.||.:.|..  ..| :.|||.:|     |.|::|.: |.|    .||.||:|||...|
 Worm     4 LSVSCLLLLHFASVLADPTYD-VTVQTPNG-----SATIRGIQ-HTYGTSFRGIRYAQPPVGLFR 61

  Fly    82 FRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRH 146
            |......:| .|:::|......|||               .......||||:|||:.|
 Worm    62 FGAARRLDP-VGLVEAQAYGNICVQ---------------GDGRTSHEDCLFINVYTP------- 103

  Fly   147 GRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNV 211
                                    |.....:.||:.::|:||||:.|...:.......:...|.:
 Worm   104 ------------------------NNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNKGPI 144

  Fly   212 IVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGES 276
            ::.|..||:|.|||.       |.....||||..:.|...|:.|::.....|||:|..:|:.|:|
 Worm   145 VMVSINYRLGPFGFF-------STRQMTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQS 202

  Fly   277 AGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNP-- 339
            :|:.:|:...::|:.:.|.|:.:.:||:.........|||.....|.|.....|..|....|.
 Worm   203 SGAEAVSTLTLTPLAKNLFKQSIHESGSAFGAAVMSYSEKTRSTSKQLSIKLGCATSDQWDNGQS 267

  Fly   340 -AHVMSCMRSVDAKTI--------------SVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKT 389
             ..:::|:|:|....|              |:.|.|.|       ....::...|..||..
 Worm   268 FGTILTCLRNVTYDKIVAADNSLPGHRMKWSIVQDNKY-------LTQRLEYLALQRDPKK---- 321

  Fly   390 ADLKDYDILMGNVRDE----------------------------GTYFLLYDFIDYFDKDDATAL 426
                  ::|:|:|.||                            |:|.:.|    :.:|......
 Worm   322 ------NVLIGDVHDEWLGWEMNNVLHNINSSHNTAHQMRDDLSGSYEMTY----WDNKQSVLVA 376

  Fly   427 PRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGN--PGYQNQQQIGRAVGD--HFFTCPTNEYAQ 487
            ..:||:    |..|......||        ||..  ..:.....||..:.|  :|.....|.|..
 Worm   377 ADNKYI----NNQGWTDDNHRE--------WEARRIQLWSEMVFIGPTLRDAAYFQYMKNNVYLY 429

  Fly   488 ALAERGASVHYYYFTHRTSTSLWGEWM--------------GVLHGDEIEYFFGQPLNNSLQYRP 538
            :|                      :|:              |..|..|::|.|.... |......
 Worm   430 SL----------------------DWLSPPALPLVTDPLFRGCEHTWELQYIFSTSC-NGFTCTA 471

  Fly   539 VERELGKRMLSAVIEFAKTGNPAQDGEEWP-NFSKEDPV--YYIFSTDDKIEKLARGPLAARCSF 600
            .:..|.....:..:.|...|||...|...| .:...|..  :..||.:.|::.
 Worm   472 QDEILRNYFTTTWLNFIIGGNPTPAGSPLPFKWLAMDSTNRFLSFSPNPKMQP------------ 524

  Fly   601 WNDYLPKVRSW---AGTCDGDSG 620
              .|.|....|   |.|.||..|
 Worm   525 --HYHPDSMFWVCTAPTIDGYKG 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	133/629 (21%)
cest-13	NP_741921.1	Abhydrolase	22..510	CDD:304388	130/604 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910