Protein Alignment Ace and nlg-1

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001257226.1
• Gene: nlg-1 / 181484
• WormBaseID: WBGene00006412
• Length: 847
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 154/638 - (24%)
• Similarity: 270/638 - (42%)
• Gaps: 132/638 - (20%)

  Fly    45 VQTSSGPVRGRSVTVQGRE---VHVYTGIPYAKPPVEDLRFRKPVPAEPW-HGVLDATRLSATCV 105
            |.||.|.|||..|:.:|.:   |..|.||||...|....||...:.|..| |...||.::|..|:
 Worm    23 VTTSWGMVRGEVVSPEGDDLPPVAQYLGIPYGVAPTGQYRFNMAISAAKWTHMPKDARKVSPVCI 87

  Fly   106 Q---------ERYEYFPGFSGEEI-WN----PN-TNVSEDCLYINVWAPAKARLRHGRGANGGEH 155
            |         :|:..|...|.:.. :|    |: ...||||||:|::.|.:..:
 Worm    88 QTDMPELSETKRFRAFKHTSAQRFDFNHRLLPHLKKQSEDCLYMNIYVPERLEI----------- 141

  Fly   156 PNGKQADTDHLIHNGNPQNTTNGLPILIWIYGG--GFMTGSATLDIYNADIMAAVGNVIVASFQY 218
                              :..|.||:::.::|.  |:.||:|    :|...:||.|::||.:..|
 Worm   142 ------------------SRDNYLPVMVIVHGEEYGWGTGNA----FNGTTLAAYGHIIVVTLNY 184

  Fly   219 RVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVN 283
            |:|.||||....      :....||.|:.|...|:..|.....:|||:.:.:||.|..:|:|.|:
 Worm   185 RLGVFGFLGRCE------SSSCSGNSGISDLVSALTMLNVILPSFGGDSKSVTLAGWGSGASLVS 243

  Fly   284 AQLMSPVT---RGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNC----NASMLKTNPAH 341
            ..:.||:|   |.|.:|.::..|:..:||:  .|:...:....|..:..|    ..|....|...
 Worm   244 LLMASPLTQPGRRLFRRAILLDGSALSPWA--ISQNPQQYFMQLAEELACAPKNRTSSFNDNVDT 306

  Fly   342 VMSCMR-----SVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKT---ADLKDYDIL 398
            ::.||:     ::....:.:......||.     ||.:||..:|..|.....|   :..::.|:|
 Worm   307 IVRCMQVHSSENITKAVLKIDVPTFLSGF-----APIVDGQLIPNKPQVSFSTQYGSLFREIDLL 366

  Fly   399 MGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAERE----AIIFQYTSWEG 459
            :| :....::.::      .::|....:.::|.:.|..::........||    :||.:||.||.
 Worm   367 VG-ISSNPSHHMI------SNEDLKVGISKEKRMRIFRSLVRNLYDFHREEILASIINEYTDWEN 424

  Fly   460 NPGYQNQQQIG--RAVGDHFFTCPTNE----YAQALAERGASVHYYYFTHRTSTSLWGEWM---- 514
            ...:....:.|  .|:.|..:|.|..|    ::.....:.|:...:.|.|.|.:  |.:..
 Worm   425 PRDHPKSIRNGVLNALSDVLYTAPLIETLRSHSADEVRKEANTFMFAFAHETRS--WSQEQPNSG 487

  Fly   515 --GVLHGDEIEYFFGQPL--NNSLQ-----YRPVERELGKRMLSAVIEFAKTGNPAQ-------- 562
              |.|.||.:.|.||.||  .:|.:     :...::.:.|.|:..|..|.|:|:|::
 Worm   488 IRGSLSGDIVPYIFGYPLAQGDSEERLYSGFNTDDKGISKVMMHYVSNFVKSGDPSKPNPMSKNF 552

  Fly   563 ------DGEEWPNFSKEDPVYYIFSTD-DKIEKLARGPLAARCSFWNDYLPKV 608
                  ....||.|.:.:...|:..|| .:::...|.   |:..|||:::|::
 Worm   553 PMGDVFHSTAWPQFDQPNREAYLEITDRPRVKNYYRN---AQVGFWNNFIPQL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	150/629 (24%)
nlg-1	NP_001257226.1	COesterase	22..595	CDD:365897	150/629 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910