Protein Alignment Ace and cest-16

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 165/680 - (24%)
• Similarity: 282/680 - (41%)
• Gaps: 170/680 - (25%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSS-----GPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRK 84
            |:|:|:...|...|   :|:.::.|     |.|||....:.|:.:.::.|:|||:||:.:|||:.
 Worm     4 LLLLLTFIFSWANG---QLLEKSRSVWVEQGLVRGNIYNIDGKHIQIFRGVPYAEPPIGELRFKP 65

  Fly    85 PVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNV---SEDCLYINVWAPAKARLRH 146
            ||....||..|.|......|:|     |..|...:.: ..||:   ||||||:||::|
 Worm    66 PVKKTRWHQELPAVEYGPPCLQ-----FMDFHKNDKF-AKTNMDRQSEDCLYLNVFSP------- 117

  Fly   147 GRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNV 211
                          .|||         :.:...|||:||:||.|:.|||...| :.:::||  |:
 Worm   118 --------------YDTD---------DESKTYPILVWIHGGSFLAGSADTGI-DMEVIAA--NI 156

  Fly   212 I-----VASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMT 271
            :     ..|..||:|..||::.      :..::..||.|:||..:|::|::.|...|.|:|..:|
 Worm   157 VSKGIAFVSINYRLGPLGFMNY------QNGDKLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVT 215

  Fly   272 LFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWS-HMTSEKAVEIGK------------- 322
            :.|||||.::.:...:||.|.||:.:.::.||:..|.|: |..|:.|..:..
 Worm   216 VMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEKWINE 280

  Fly   323 ----------------ALINDCNCNASMLKTN-------PAHVMSCMRS-------VDAKTISVQ 357
                            ::|....||...:|.|       ....|:|:|.       :..|.::.:
 Worm   281 DDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKMNCLRKELNFSSPLFRKALAAE 345

  Fly   358 QWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTY--FLLYDF--IDYF 418
                 .|:    |...:||..:|:..::|::  :.....|:.|..|.|..:  .:.|:.  .|..
 Worm   346 -----LGV----SKMVVDGDLVPSSGVSLVR--NNARIPIMTGVARKEWGHKKAMFYNMHQRDGL 399

  Fly   419 DKDDATALPRDKYLEIMNNIFGKATQAER----------EAIIFQYTSWEGNPGYQNQQQIG--- 470
            .:.|.    .::...|::|.|.: |.:|:          .|.|.:|.....|. :...|.:|
 Worm   400 KRSDV----EEQVYRIIDNSFHE-TASEKLANSTVQLIANATIVRYLETPNNE-FIADQVVGALQ 458

  Fly   471 RAVGDHFFTCPTNEYAQALAERGASVHYYYF----------THRTSTSLWG---------EWMGV 516
            :...|..|..|......|..::|..|:.|.|          :.|...||:|         |...:
 Worm   459 KLESDIEFVAPCEREVAAYVDKGVPVYLYSFDYVPKSPILESERKIYSLFGTKPVEMKRTEKSEI 523

  Fly   517 L-----HGDEIEYFFGQPLNNSLQYRPV---ERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKE 573
            |     ||.:..:.|.:..:::.:..|.   |..:.|.:.:.:..|.|.|:|:.....||.||..
 Worm   524 LEKAAFHGLDHAFIFSKGYSSNFEISPYTKREETMSKILCTMLTNFVKNGDPSTTRFSWPIFSGN 588

  Fly   574 DPVYYIFSTDDKIEKLARGPL-AARCSFWN 602
            ...|  .|.|..: ||..|.: .....|||
 Worm   589 SSQY--VSLDVPL-KLLEGEIHFPDAQFWN 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	157/661 (24%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	156/647 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810