Protein Alignment Ace and cest-2.3

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 134/587 - (22%)
• Similarity: 247/587 - (42%)
• Gaps: 108/587 - (18%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQ-----GREVHVYTGIPYAKPPVEDLRFRK 84
            |...:.:|||    :..|  :|.|:|.:.|:.:...     .:...|:.||||.:||:.:|||||
 Worm     6 LYFAVLIHLS----ISTR--IQLSTGTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRK 64

  Fly    85 PVPAEPWHGVLDATRLSATCVQE-RYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGR 148
            |...:.|.|||:.......|:.. |..:..||.||        :||||||.||:.
 Worm    65 PRLLKSWEGVLETKDYKPACMSYWRKTFKNGFVGE--------ISEDCLYANVFT---------- 111

  Fly   149 GANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFM--TGSA-TLDIYNADIMAAVGN 210
                          ..:.:.|.|       ..::|.::||..:  :||| ..:|:..:.:....|
 Worm   112 --------------NQYCLQNKN-------CSVMIVVHGGRLVCESGSAFKPEIFINNFVGQDRN 155

  Fly   211 VIVASFQYRVGAFGFLHLAPEMPSEF-AEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFG 274
            ::|.:|.||:|.|||        ..| .|....||.::|...|::|::.....||||.:.:|:.|
 Worm   156 IVVVTFNYRLGVFGF--------GVFNGETGDTNVAMYDMLEAVKWVRKEIDQFGGNKDRITMAG 212

  Fly   275 ESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALI-NDCNC-------- 330
            .|||:..:.....|.:::||    :.|...|:||...: |:.|...|..:: .:..|
 Worm   213 HSAGAGLIVDFTSSTLSKGL----LHQQIVMSAPLQDI-SKSANFKGMTIVAQNVGCIPKEYGFR 272

  Fly   331 NASMLKTNPAHVMSCMRSVDAK-----TISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTA 390
            ..|..:.|..::  |:::..|:     .:|:||.:::     :..:|.:||.|:...|..|....
 Worm   273 KLSKTQINKTYL--CLQNKSAQDLLHAQLSMQQNSTF-----YFGSPRVDGDFITDYPDNLFNFN 330

  Fly   391 DLKDYDILMGNVRDEGTYFLLYDFIDYFD-KDDATALPRDKYLEIMNNIFGKATQAEREAIIFQY 454
            .:...:..:|....|     |.|.:...| |:|..   :::.|:.|....|.....:.|    ::
 Worm   331 TIYPINTFIGTTTGE-----LRDSLYITDPKNDRI---KEQLLKNMCEHVGYELFEKPE----EF 383

  Fly   455 TSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWM---GV 516
            |...|| .|:|.........|..|.....:.|.|.....:.|..|.:.::.:.:.:.:::   ..
 Worm   384 TKKCGN-YYKNGTDAQFLSDDMEFYSGAIKVANAHKRANSKVFMYSYDYKGAGTAFHKYLEAPSP 447

  Fly   517 LHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFS 581
            .|.:::.|.||......:....|...:...||:..|.| :..:|::. ::|..:::|...|::..
 Worm   448 HHSEDLIYTFGTSRGPFVAKDYVIERIYSGMLANFINF-EDPSPSKT-QQWRQYTQEKREYFLID 510

  Fly   582 TD 583
            .|
 Worm   511 FD 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	129/569 (23%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	130/572 (23%)