Protein Alignment Ace and cest-1.1

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 153/653 - (23%)
• Similarity: 270/653 - (41%)
• Gaps: 146/653 - (22%)

  Fly    22 PLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQ-----GREVHVYTGIPYAKPPVEDLR 81
            |..::|::.::   ||     ..||.|||.:.|:.:.:.     .:...|:.|||:.:||:.|||
 Worm     4 PATVLLLIQMY---VC-----KRVQLSSGTIEGKILNISYSPLGNQSATVFLGIPFVEPPIGDLR 60

  Fly    82 FRKPVPAEPWHGVLDATRLSATCVQERYE-YFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLR 145
            :|||.|.:.|.|||......:.|:....: |...|.|.        :||||||:||
 Worm    61 YRKPRPPKSWEGVLVTNEYKSACMSNATKTYKNKFGGP--------ISEDCLYLNV--------- 108

  Fly   146 HGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMA--AV 208
                           ...::.:.|.|       ..:::.::|||::|.||:  .:|.:|:.  .|
 Worm   109 ---------------LTNEYCLENKN-------CSVMMIVHGGGYLTESAS--TFNPEILINNFV 149

  Fly   209 G---NVIVASFQYRVGAFGFLHLAPEMPSEF-AEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEW 269
            |   |::|.:|.||:|.|.|        .:| .:....|.||:|...::.|::.....||||...
 Worm   150 GQGRNIVVVTFNYRLGLFSF--------GQFNGDRGDKNFGLYDMIESVNWVRREIENFGGNKNR 206

  Fly   270 MTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASM 334
            :||.|.|||:|.:.|...||:|:|||.:.::    |:||.::|:.:...:....:.....|.:..
 Worm   207 ITLAGHSAGASMIVAFTSSPLTKGLVHQQII----MSAPMTNMSKKSNFKGMTVMAQMVGCLSEE 267

  Fly   335 LKTNP------AHVMSCMRSVDAKTI-SVQQW----NSYSGILSFPSAPTIDGAFLPADPMTLMK 388
            :..|.      .:..||:|...|:.| ..|.|    ::|     |..||.||..||...|..|..
 Worm   268 IGFNKLSEEQVENTYSCLRKKSAQQILDAQLWLLQNSTY-----FLGAPPIDEHFLTDYPENLYA 327

  Fly   389 TADLKDYDILMGNVR---DEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNI------------ 438
            :..:...:.|:|...   :|.:|.:          |.|.|   ||.:|::.|:
 Worm   328 SKSIYPINTLIGTTTLEVEESSYII----------DPAFA---DKKVELLENLCDHIGYVLYEEP 379

  Fly   439 --FGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYF 501
              |.|..|.       ||.:...:....|:.:        |:| |..::|.:.......|..|.:
 Worm   380 ETFSKKCQK-------QYMNGNSSMNLSNEME--------FYT-PAIDFADSHTSGNTKVFLYSY 428

  Fly   502 THRTSTSLWGEWMGVL---HGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQD 563
            .:|.:...:..::.|.   |.:::.|.||   .:...:.|.:..:.|.......:|....||...
 Worm   429 DYRGAGPAYDRYLEVRSPHHSEDLIYVFG---THRGIFAPKDYIIEKIYSGMFADFVNFENPLPS 490

  Fly   564 GEE-WPNFSKEDPVYYIFSTDDKI--EKLARGPLAARCSFWNDYLPK--VRSWAGTCDGDSGSAS 623
            |:: |..::||:..:::.:.|...  ..:..........||:....|  ...|:.:.|..:.:..
 Worm   491 GDQKWNQYTKENREHFLINFDKNFITPGMRDNYYTEAYEFWSTVGKKSFKEEWSPSLDTFTCALV 555

  Fly   624 ISP 626
            |||
 Worm   556 ISP 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	141/605 (23%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	141/601 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910