Protein Alignment Ace and cest-33

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 167/602 - (27%)
• Similarity: 257/602 - (42%)
• Gaps: 125/602 - (20%)

  Fly    45 VQTSSGPVRGR-----SVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATC 104
            ::.|.|||||.     .|.|.|     |.|||||||||.:|||:|||..:.|..:.|..:....|
 Worm    17 LKASCGPVRGNIYKHDDVIVDG-----YLGIPYAKPPVGELRFKKPVTVDVWTEIKDCYKYGPAC 76

  Fly   105 VQERYEYFPGFSGEEIWNPNTNVSED--CLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLI 167
            ||.     .||  |:|..|.|...|:  ||.:||:.|..|         ..|..||:
 Worm    77 VQT-----GGF--EQIAGPRTPTPEEAGCLTLNVFTPRNA---------SSEFKNGR-------- 117

  Fly   168 HNGNPQNTTNGLPILIWIYGGGF-MTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPE 231
                        |::::|:|||: :..|:....|:......:.:|:|.|..||:|.||||.....
 Worm   118 ------------PVMVYIHGGGYELCASSDFCAYSLSGTLPLKDVVVVSINYRLGVFGFLTTGDN 170

  Fly   232 MPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVK 296
            :       .|||.|||||.||::|::.:..:|||:|..:|:||:|||.:|.:...:||.:|.|.:
 Worm   171 V-------CPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSAGGASTDLLSLSPHSRDLFQ 228

  Fly   297 RGMMQSGTMNAPWSHMTSEKAVEIGKALI-------NDCNCNASMLKTNPAHVMSCMRSVDAKTI 354
            |.:..|||.:..::...||...:|.:...       .|.:......:......:|.::...
 Worm   229 RFIPISGTAHCDFAIRASENQAKIFREFAEFHGFSGRDSSALFKWYQEQSPETLSNVKGYK---- 289

  Fly   355 SVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFD 419
                 .|.||.|:|  .|.:||.|.|.....|.|.|..|  .::.|....||  .:|......|.
 Worm   290 -----KSISGFLTF--IPNLDGDFFPKPLDELRKEAPKK--QMMTGVTEYEG--LMLASMNPAFS 343

  Fly   420 KDDATALPRDKYLEIM-NNIFGKATQAEREAI--IFQYTSWEG---NPGYQNQQQIGRAVGDHFF 478
                   |.|..|.:| ..|:||...:..:.|  ||.....||   :.....::::..|:||.||
 Worm   344 -------PADVGLTLMPQGIYGKDVVSNPDEIQKIFYEKYVEGVDKSDELAMRKKLCEALGDEFF 401

  Fly   479 TCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVL------HGDEIEYFFGQPLNNSLQYR 537
            .....:.|:..|:.|..|::|.|.:....| :|.|.|::      |..|:.|..|:.:.:..:..
 Worm   402 NVGVIQAAKNAAKHGNEVYFYTFEYVNPDS-FGMWDGMMPFKAAVHCTELRYLLGEGVYSKFEPT 465

  Fly   538 PVERELGKRMLSAVIEFAKTGNPAQDG---EEWPNFSKEDP---------------VYY------ 578
            ..:|::.:...:....|||.|||...|   |.|..:|...|               ||:
 Worm   466 EEDRKVMETTTTLFSNFAKYGNPNGKGATAEIWEKYSLNRPERHYRISYPKCEMRDVYHEGRIQF 530

  Fly   579 ---IFSTDDKIEKLARG 592
               |....||.::|..|
 Worm   531 LEKIDGDSDKYQELVYG 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	167/602 (28%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	160/574 (28%)