Protein Alignment Ace and cest-35.1

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 147/560 - (26%)
• Similarity: 241/560 - (43%)
• Gaps: 87/560 - (15%)

  Fly    44 VVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQER 108
            |:..|.||:||.......:.|..|.|||:||.|:.:|||:|.|.||.|...||..:....|.|.
 Worm    16 VLNASCGPIRGNIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGPGCPQS- 79

  Fly   109 YEYFPGFSGEEIWNPNTNVSE----DCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHN 169
                 |..|..|....:.:.|    :||.:||:||.         ....|.|
 Worm    80 -----GALGAMIVPQASAIREFAEDNCLTLNVFAPK---------WKSAEFP------------- 117

  Fly   170 GNPQNTTNGLPILIWIYGGGFMTG-SATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMP 233
                   ||||::::.|||||..| |:..|.|:......:.:||:.:..||:|..||.....::
 Worm   118 -------NGLPVIVYFYGGGFEVGFSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDV- 174

  Fly   234 SEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRG 298
                  :.||.||||||||::|::.:..:|||:|..:|:.|.|||.:||:...:||.......:.
 Worm   175 ------SRGNWGLWDQALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKF 233

  Fly   299 MMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSY- 362
            :..||....|:    ..::.::...:..:...:......:...::...:|.||:.....:...|
 Worm   234 IPMSGAATCPF----GIRSKDVEGLIFREFAKHHGYAGNDSESLLHWYQSQDAEIFLKAEGFKYP 294

  Fly   363 -SGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYF--DKDDAT 424
             ||:.||  .|..||.|.|.....|.|.|...|..:.:......|       |.:::  .|....
 Worm   295 ASGMFSF--VPNYDGDFFPKPFDELRKEAPKLDAIVSVAEYEGLG-------FEEFYPGQKSPQE 350

  Fly   425 ALPRDKYLEIMNN---IFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYA 486
            .|......|::.|   :..||.:|..|.|       |...|.:..:::....||::|:....:..
 Worm   351 VLTAALGPEVVRNREEVVKKAVEAYLENI-------EDKSGEKIGKKLVEIFGDYYFSVGVFDTV 408

  Fly   487 QALAERGASVH---YYYFTHRTSTSLWGE---WMGVLHGDEIEYFFGQPLNNSLQYRPVERELGK 545
            ::||:.|.:|:   :.||...|.. ::||   :....||.:|.|..|..:.   ::...:|::..
 Worm   409 RSLAKYGNNVYLSSFNYFNPETPI-MFGENRPFNAASHGCDIRYILGDGIG---EFSKEDRKVMD 469

  Fly   546 RMLSAVIEFAKTGNPAQDGEE--WPNFSKEDPVYYIFSTD 583
            .|.:.:..|||.|||...|..  |..:|.::|..| |..|
 Worm   470 MMGTYLTNFAKYGNPNGKGVSIPWEKYSLDNPGRY-FKID 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	147/560 (26%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	147/560 (26%)