Protein Alignment Ace and cest-6

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 629
• Identity: 132/629 - (20%)
• Similarity: 227/629 - (36%)
• Gaps: 209/629 - (33%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAE 89
            |::|.|.:.|...|||     .||.|.:.|..:    .....:..||:||||:..|||:||:.||
 Worm    11 LLIVYSAYKSCEAGVI-----TTSLGSINGNQI----GSYQTFKKIPFAKPPIGKLRFQKPMAAE 66

  Fly    90 PWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGE 154
            .|.|:|:||.....|:.         :.....:|...:.||||:||::.
 Worm    67 KWEGILNATEYGPACMS---------NSSTSKSPQKWIDEDCLHINIFT---------------- 106

  Fly   155 HPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATL--DIYNADIMAAVGNVIVASFQ 217
                    ||..:.:.|       ..::.:::||..:..||.:  |.|..|..:: .:||:....
 Worm   107 --------TDTCLSSKN-------CSVVFYVHGGELVYDSAVMFEDKYLFDTFSS-RDVILVIPA 155

  Fly   218 YRVGAFGFLHLAPEMPSEFAEE----APGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAG 278
            :|:|.|          |.|..|    ||.|:.|:|..||:.::|...|.|||:.:.:|.||.|.|
 Worm   156 FRLGLF----------SHFVVEDQNVAPNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHSYG 210

  Fly   279 ---------SSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASM 334
                     |:.:|..|      ...:|.:..| ::|. |..:..|  :|.....|...||:...
 Worm   211 GHVVSVMAFSTEINTDL------SYFQRVICMS-SVNV-WDSLEFE--IEKTMRFIQYANCSVPQ 265

  Fly   335 -LKT------NPAHVMSCMRSVDA-------KTISVQQWNSYSG-ILSFP--------------- 369
             ||:      ..:::|.|::.:|:       :::..:....||| :|..|
 Worm   266 DLKSRMTSFEQDSYMMECLQDIDSMELLRIQRSLEDEGHPIYSGLVLREPLIQNVLVQDFYEKPK 330

  Fly   370 SAPTIDG-AFLPADPM----TLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRD 429
            :.||:.| .:...|..    .:::|...::|.......||:..|. .:|...:.|:
 Worm   331 NIPTLTGCTYKELDKFHAYHNIVETLGYENYKECDDKYRDDRKYG-RFDLNKHADE--------- 385

  Fly   430 KYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGA 494
                    .||...|.:.:.                .:|:.:.:..:|:
 Worm   386 --------TFGILAQTKLKV----------------DKQLDKGIPTYFY---------------- 410

  Fly   495 SVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGN 559
              .|.|..|.:            |.|::.|..|.   ::.:....|..|.|......:.|.|.|.
 Worm   411 --EYSYPKHPS------------HTDDLSYIMGV---HAFEKDENEIHLAKSYQEMFMNFVKFGE 458

  Fly   560 PAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWND 603
            |. .|.|...|  |:..|:.|                   :||:
 Worm   459 PG-GGFEMSTF--ENSSYFNF-------------------YWNE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	123/609 (20%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	127/615 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910