Protein Alignment Ace and cest-4

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 139/594 - (23%)
• Similarity: 216/594 - (36%)
• Gaps: 167/594 - (28%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAE 89
            |:|.||..|  :..:....:|.||.|.:.|..:    ...|::..||.||||:..|||:||.|.|
 Worm    11 LLLFLSFFL--LFSITKSAIVSTSLGQIDGDQI----GSFHLFKHIPLAKPPIGKLRFQKPEPPE 69

  Fly    90 PWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGE 154
            .|.||.:|......|:.         :.....:|...:.||||:||::...|..
 Worm    70 KWTGVRNAKAYGPACIS---------NSSVSTSPQKWIDEDCLHINIFTSDKCL----------- 114

  Fly   155 HPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATL--DIY------NADIMAAVGNV 211
                |..|                ..::.:.:|||.|..||.:  |.|      |.|       |
 Worm   115 ----KSKD----------------CAVVTYFHGGGLMYDSAVMFNDTYLLGTFVNQD-------V 152

  Fly   212 IVASFQYRVGAFGFLHLAPEMPSEFAEE----APGNVGLWDQALAIRWLKDNAHAFGGNPEWMTL 272
            |:|...:|:|.|          |.|..|    ||.|:.|:|..|.:.::|:..|.||||.:..|:
 Worm   153 IIAIPAFRLGIF----------SHFVVEDQSIAPTNLALYDILLGVEFVKNEIHNFGGNNQKNTI 207

  Fly   273 FGESAGSSSVN-AQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASML- 335
            .|.|.|.|.|| ....|.:...|..  ..||..|::.....|.|..::..........|....:
 Worm   208 MGHSYGGSIVNILTFSSKINHDLSL--FQQSICMSSGHDFETLEIQIQKTNRFAKHAGCTVPSII 270

  Fly   336 ------KTNPAHVMSCMRSVDA-KTISVQQWNSYSGILSFPSAPTIDGAFLPADPM-------TL 386
                  :.:..:.|.|:::.|| :.:.||:      :|.....||. |..:..:|:       ..
 Worm   271 EKKMTTRQSDLYRMKCLQNKDALELLRVQR------LLEDEGYPTY-GYLVQREPLIQEIPYQEF 328

  Fly   387 MKTADLKDYDILMGNVRDEGTYFLLYDFIDY--FDKDDATAL----PRDKYLEIMNN------IF 439
            ||:.  |...:|.|..|.|         :|:  ..|....||    |.:.|::...:      .|
 Worm   329 MKSP--KKIPMLTGCTRYE---------MDHSPAPKPIGQALGFENPEEVYMKFRKDWDDEVYEF 382

  Fly   440 GKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHR 504
            |..:. |.:||:.|......|                            |..:....:.|.:|:.
 Worm   383 GNHSD-ETQAIMVQVRVRVNN----------------------------LLSKNVPAYLYEYTYP 418

  Fly   505 TSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPN 569
            ....         |.|::.|..|.   :..:....|.||||...:..:.|||.|:| ::|.|..|
 Worm   419 KHAR---------HTDDLFYLMGV---HRFEKDENEIELGKVYETIFMNFAKFGDP-KEGFELAN 470

  Fly   570 FSKEDPVYY 578
            ...|.  ||
 Worm   471 AENES--YY 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	134/578 (23%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	134/575 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910