Protein Alignment Ace and ace-2

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 180/566 - (31%)
• Similarity: 274/566 - (48%)
• Gaps: 96/566 - (16%)

  Fly    44 VVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQER 108
            ||.|..|.:||...|..|.:|..:.|:||||||:...||:.....:.|.|.|:|..|:.||....
 Worm    40 VVHTPLGTIRGVGQTFDGAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTCYLTI 104

  Fly   109 YEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQ 173
            ...||.|.|.|:|||...:|||||.:|:|.|..                          |:|:
 Worm   105 DSAFPQFPGAEMWNPPGAISEDCLNMNIWVPED--------------------------HDGS-- 141

  Fly   174 NTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAE 238
                   :::|||||||.:|:.:||:|:..:.||..:.||.:..||:|.||||:...:.|.:
 Worm   142 -------VMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFGDDSPIQ--- 196

  Fly   239 EAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSG 303
               ||:||.||.||:||:.:|..||||:...:|||||||||:|..|.|.:|.:....:..:.:||
 Worm   197 ---GNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSG 258

  Fly   304 TMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGI--- 365
            ::...|:..|....:::...|....||::..:..    ::.|:|||.|..:..:..|....|
 Worm   259 SIINSWASATPPTMLDLSFRLAKKVNCSSPDMNA----IVKCLRSVPAHLVQAEADNISGDIGPP 319

  Fly   366 LSFPSAP-TIDGAFLPADPMTLMKTAD---LKDYDILMGNVRDEGTYFLLY------------DF 414
            ::|...| :.|..|...|  ...|.|:   .||.:|:.|:|:|||||:|.|            ..
 Worm   320 MTFAYVPVSSDANFFQGD--VFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPKYGFAFNHT 382

  Fly   415 IDYFDKDDATALPRDKYLEIMN-------------NIFGKATQAEREAIIFQYTSWEGNPGYQNQ 466
            |...|..:...:.||.|.|.|.             |.|..:         :::.|....|..:.:
 Worm   383 ISAEDPHNRALITRDHYEESMRAFMPYFAGSKLVLNAFMNS---------YEHVSTSNVPEERYR 438

  Fly   467 QQIGRAVGDHFFTCPTNEYAQALAER-GASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPL 530
            ..:.|.:||.||||...::|..:::. ..:|:.||||:|:|.:.|.:||||:||.||||.||||.
 Worm   439 DGVARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRSSANPWPKWMGVMHGYEIEYAFGQPY 503

  Fly   531 NNSLQYRPVERELGKRMLSAVIE----FAKTGNPAQDGEEWPNFSK 572
            .....|.....|..||:.|.:::    ||.||   :....||.::|
 Worm   504 WRPHLYDQTHLEDEKRLSSIIMQIWANFANTG---RTDSFWPQYNK 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	180/566 (32%)
ace-2	NP_491141.1	COesterase	33..546	CDD:278561	179/564 (32%)
		Aes	<135..>233	CDD:223730	47/138 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165228
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45275
OrthoDB	1	1.010	-	-		D339133at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43918
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.820