Protein Alignment Ace and cest-27

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 150/612 - (24%)
• Similarity: 244/612 - (39%)
• Gaps: 130/612 - (21%)

  Fly    44 VVQTSSGPVRGRSVTVQ-GREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQE 107
            |...:.||::|.....: |..|..:.|||||:||:..|||:|||....|...||..|......|
 Worm    27 VHDATCGPIKGVGYEQEDGSVVEGFLGIPYAEPPIGALRFKKPVAHRKWTEPLDCVRFGPRSPQ- 90

  Fly   108 RYEYFPGFSGEEIWNPNTNV----SEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIH 168
                     .:|:.....|.    .|.||.:||:.|.         ....|.|
 Worm    91 ---------NDELLGQFVNTVGKSEEHCLSLNVFTPK---------WESNEWP------------ 125

  Fly   169 NGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMA---AVGNVIVASFQYRVGAFGFLHLAP 230
                    :|.|::::|:||||...|::  .|....:|   ...:|:|.:..||:|..||.....
 Worm   126 --------DGFPVMVFIHGGGFAVHSSS--NYGCASIARNLCTKDVVVVTINYRLGVLGFFTTGD 180

  Fly   231 EMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLV 295
            |:       ..||:|||||..|:.|:::|..:|.|:|:.:|:||:|||.:||:...:||.:|||.
 Worm   181 EV-------CRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQSAGGASVDLLCLSPHSRGLF 238

  Fly   296 KRGMMQSGTMNAPWSHMTSEKAVEIGKALI------NDCNCNASMLK-------------TNPAH 341
            .|.:..:|.....::..|||:..::.:...      .|.|.:..:|:             .||..
 Worm   239 NRAIPMAGNGECDFAMRTSEQQAQLSREFARYLGWEGDDNDSEDLLQFIDQQPLYKIEMGINPKR 303

  Fly   342 VMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEG 406
            ...               :|.:|.|.|  .|..||.|.|.....|.|.|  ....|:.|..:.||
 Worm   304 GFK---------------HSQAGSLYF--VPNFDGDFFPKPLNQLRKEA--PKMQIMTGTTKYEG 349

  Fly   407 TYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAII------FQYTSWEGNPGYQN 465
            .:|:..         .|.:...:...:.|..||.:....||...:      |.:.........:|
 Worm   350 LFFIAL---------GALSKNPEGIKKFMGRIFKECDYGERADDVLQMVYDFYFKGVHPKDHEKN 405

  Fly   466 QQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWG--EW----MGVLHGDEIEY 524
            ..||.:.:||:.....|...|..:.:....|::|.|.:..|.. :|  .|    :|..|..|:.|
 Worm   406 MHQIVKFIGDYSINYGTYRLANIMTDLQHDVYFYQFDYHNSAG-FGVFRWLLPFLGSTHCTEMRY 469

  Fly   525 FFGQPLNNSLQYRPVERELGKRMLSAV----IEFAKTGNPAQDGEEWPNFSKEDPVYYI--FSTD 583
            ..|:.:.:  ::||.:.:  |:||..:    ..|||.|||..:.:|...:.|.|..:..  |..|
 Worm   470 VLGKGIIS--KFRPNDND--KKMLHVMTTYFTNFAKYGNPNGENQETGEWQKHDSAHPFRHFKID 530

  Fly   584 DKIEKLARGPLAARCSFWNDYLPKVRS 610
            ....::.......|...|:    |:|:
 Worm   531 LDDSEMVEDYQERRAELWD----KLRA 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	147/601 (24%)
cest-27	NP_871861.2	COesterase	29..548	CDD:395084	146/599 (24%)