Protein Alignment Ace and Ces3b

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_653094.2
• Gene: Ces3b / 13909
• MGIID: 3644960
• Length: 571
• Species: Mus musculus
• Alignment Length: 632
• Identity: 175/632 - (27%)
• Similarity: 273/632 - (43%)
• Gaps: 133/632 - (21%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQ----TSSGPVRGRSVTVQ--GREVHVYTGIPYAKPPVEDLRFR 83
            ||.|..|.|:.|..|....|:|    |..|.||||.|.|:  .|.|:|:.|||:|:.||..|||.
Mouse    15 LVWVTCLLLAFVTTVTGPKVIQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPVGPLRFS 79

  Fly    84 KPVPAEPWHGVLDATRLSATCVQ-------------ERYEYFPGFSGEEIWNPNTNVSEDCLYIN 135
            .|:|.:||.||.||:.....|:|             |:.:.||             :|||||.:|
Mouse    80 APLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIKIFP-------------ISEDCLTLN 131

  Fly   136 VWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIY 200
            :::|.:                         |..|:.:      |:::||:||..:.||:|..
Mouse   132 IYSPTE-------------------------ITAGDKR------PVMVWIHGGSLLVGSSTSQ-- 163

  Fly   201 NADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGG 265
            :...:||.|:|:|.:.|||:|.||||       |...:..|||.|..|...|:||::.|...|||
Mouse   164 DGSALAAYGDVVVVTVQYRLGIFGFL-------STGDKHMPGNRGFLDVVAALRWVQGNIAPFGG 221

  Fly   266 NPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNA-------PWSHMTSEKAVEIGKA 323
            :|..:|:||.|||...|::..:||::.||..|.:.|||.:..       ||..         .:.
Mouse   222 DPNCVTIFGNSAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPWPE---------AQN 277

  Fly   324 LINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWN---SYSGILSFPSAPTIDGAFLPADPMT 385
            ..|...|.::    :||.::.|:...:.|.: ::|.|   ||          .::.:|.|..|..
Mouse   278 FANSVACGSA----SPAELVQCLLQKEGKDL-IKQKNVNISY----------IVNDSFFPQRPEK 327

  Fly   386 LMKTADLKDYDILMGNVRDEGTYFLL-----YDFIDYFDKDDATALPRDKYLEIMNNIFGKATQA 445
            |:..........|:|....|..:.||     .|.:::..::|...:.| .:|.||     :....
Mouse   328 LLADQQFPTVPYLLGVTNHEFGWLLLKSLNILDKLEHLSREDLLEISR-PFLAIM-----EVPPE 386

  Fly   446 EREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTST--S 508
            ....:|.:|.. .|:.....:......:||..|..||..:::.|.:.|..|..|.|.|..|:  .
Mouse   387 IMPTVIDEYLD-NGSDQSATRYAFQELLGDISFIIPTLNFSKYLRDAGCPVFLYEFQHTPSSFAK 450

  Fly   509 LWGEWMGVLHGDEIEYFFGQPL---NNSLQYRP----VERELGKRMLSAVIEFAKTGNPAQDG-E 565
            ....|:...|..|..:.||.|.   .:||...|    .|::|...|::...:||:||||...| .
Mouse   451 FKPAWVKADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLP 515

  Fly   566 EWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLP-KVRSW 611
            .||..::.:....|........||.:|    |..||.:.|| |::.|
Mouse   516 PWPQLNQLEQYLEIGLESRTGVKLKKG----RLQFWTETLPRKIQEW 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	162/601 (27%)
Ces3b	NP_653094.2	COesterase	36..547	CDD:395084	161/598 (27%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571