Protein Alignment Ace and LOC1282064

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_322067.4
• Gene: LOC1282064 / 1282064
• VectorBaseID: AGAMI1_003264
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 672
• Identity: 184/672 - (27%)
• Similarity: 283/672 - (42%)
• Gaps: 173/672 - (25%)

  Fly    25 LVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSV-----TVQGREVHVYTGIPYAKPPVEDLRFRK 84
            :|::.|:...|  ...|:|.:....|   ||.:     |..|:.:..:.||||||||:||||||.
Mosquito    19 IVIITSITTDG--RTSDKLKITLPHG---GRLIGRYLNTFSGQGILAFLGIPYAKPPIEDLRFRA 78

  Fly    85 PVPAEPWHGVLDATRLSATCVQ-ERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGR 148
            |||..||.|.|.||..|..|.| :.|......||          .||||::||:.|
Mosquito    79 PVPYGPWSGDLMATTDSPLCTQRDPYRRDESISG----------VEDCLHLNVYVP--------- 124

  Fly   149 GANGGEHPNGKQADTDHLIHNGNPQNTTNGL--PILIWIYGGGFMTGSATLDIYNADIMAAVGNV 211
                 |.|.....|.          |.|:.:  |::::.:|||:..||.|...|..|.:.. .:|
Mosquito   125 -----ERPRSLSVDA----------NMTHPVLFPVMVFFHGGGWQCGSGTRSFYGPDFLLE-HDV 173

  Fly   212 IVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGES 276
            |.....:|:|..|||       |....:.|||.||.||:|.:||:.:|..:|||:|:.:|:||||
Mosquito   174 IYIGANFRLGPLGFL-------STEQVDCPGNNGLKDQSLVLRWINENIASFGGDPKSVTIFGES 231

  Fly   277 AGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSH-----MTSEKAVEIGKALINDCNCNASMLK 336
            ||.:|....:|||:::||..|.:.|||.....|:.     :...:::::||.|    .|.    |
Mosquito   232 AGGASGTYHMMSPLSKGLFHRVISQSGVNLDAWAQPAHPGVARSRSIQLGKML----KCT----K 288

  Fly   337 TNPA---HVMSCMRSVDAKTISVQQWNSY----SGILSFPSA--PTIDGAFLPADPMTLMKTADL 392
            ||..   .::.|:|.|.|:.|:.:.::.|    ..::.||..  |.|.|||:...|.
Mosquito   289 TNDGSYIEMLDCLRRVPAEEITRKFYDFYLWDTDPMIPFPPVIEPDIPGAFITKHPR-------- 345

  Fly   393 KDYD-------ILMGNVRDEGTY---------FLLYDFIDYFDKDDATALPRDKY---------- 431
            .:|:       .:.|...|||..         .|.....|::|:    |||...|
Mosquito   346 DEYEPHAIELPWMTGLTFDEGALKSASLINIPELRKSLNDHWDR----ALPISLYYDHHEPEMQR 406

  Fly   432 --LEIMNNIFGK----ATQAEREAIIFQYTSW--EGNPGY-------QNQQQIGRAVGDHFFTCP 481
              .:.:|:.:.|    .|..||........:|  .|...|       .|::.....||:.:....
Mosquito   407 QITQKINSFYFKNQKLVTATERNLTNLYSDAWFLAGMDEYLRIRLLGHNKRNSTLKVGETYVYLF 471

  Fly   482 TNEYAQALAE--RGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFF--GQPLNNSLQYRPVERE 542
            ..:.:.:..|  :|.:.:||               ||.|.:|::|.|  .:.:.|.....|.|.|
Mosquito   472 AQKASASFTEIFKGGAENYY---------------GVCHAEELQYIFPIAKEIPNFQTAIPTEDE 521

  Fly   543 LGKR--MLSAVIEFAKTGNPAQDGEEWPNFSKED------------PVYY-----IFSTDDKIEK 588
            |..|  :|...|.||:||||. .|:|..|.|.::            |:.|     :.|:.:.|..
Mosquito   522 LEIRRVILKLWINFARTGNPT-PGDEKDNTSAQNQLLPQWRPADSFPLRYLRIGRLDSSKEPIVA 585

  Fly   589 LARGPLAARCSFWNDYLPKVRS 610
            |..|....|.:||.    |:|:
Mosquito   586 LETGLFEERAAFWR----KLRA 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	176/643 (27%)
LOC1282064	XP_322067.4	COesterase	41..598	CDD:395084	175/637 (27%)