Protein Alignment Ace and Cel

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 636
• Identity: 187/636 - (29%)
• Similarity: 279/636 - (43%)
• Gaps: 106/636 - (16%)

  Fly    25 LVLVLSLHLSGVCGVIDRL-VVQTSSGPVRG---RSVTVQGREVHVYTGIPYAKPPVEDLRFRKP 85
            |.|.|:..|:..|..  :| .|.|..|.|.|   :...:.|..|.::.|||:|.....:...|.|
Mouse     7 LFLGLTCCLAAACAA--KLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRHP 69

  Fly    86 VPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGA 150
                .|.|.|.||.....|:|           ..|...||...|||||:|:|.|      .||
Mouse    70 ----GWQGTLKATNFKKRCLQ-----------ATITQDNTYGQEDCLYLNIWVP------QGR-- 111

  Fly   151 NGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSA------TLDIYNADIMAAVG 209
                    ||..     ||         ||:::|||||.|:.||.      ...:|:.:.:|..|
Mouse   112 --------KQVS-----HN---------LPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRG 154

  Fly   210 NVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFG 274
            ||||.:|.||||..|||       |......|||.||.||.:||.|:|.|..||||:|:.:|:||
Mouse   155 NVIVVTFNYRVGPLGFL-------STGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFG 212

  Fly   275 ESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNP 339
            ||||::||:.|.:||..:||::|.:.|||...:||:  ..:..:...|.:.....|...    :.
Mouse   213 ESAGAASVSLQTLSPYNKGLIRRAISQSGMALSPWA--IQKNPLFWAKTIAKKVGCPTE----DT 271

  Fly   340 AHVMSCMRSVDAKTISVQ-----QWNSYSGILSFPSAPTIDGAFLPADPMTLM-KTADLKDYDIL 398
            ..:.:|::..|.:.:::.     :...|..:......|.|||.|:|.||:.|. .|||: ||...
Mouse   272 GKMAACLKITDPRALTLAYKLPVKKQEYPVVHYLAFIPVIDGDFIPDDPINLYNNTADI-DYIAG 335

  Fly   399 MGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGY 463
            :.|:  :|..|...| :...||...|....|.|..:..:...|..:..:........||..:|..
Mouse   336 INNM--DGHLFATID-VPAVDKTKQTVTEEDFYRLVSGHTVAKGLKGAQATFDIYTESWAQDPSQ 397

  Fly   464 QNQQQIGRAV-GDHFFTCPTNEYAQALAE-----RGASVHYYYFTHRTSTSLWGEWMGVLHGDEI 522
            :|.::...|. .|..|..||.   .|||:     :.|..:.|.|:|.:...::.:|||..|.|::
Mouse   398 ENMKKTVVAFETDVLFLIPTE---IALAQHKAHAKSAKTYSYLFSHPSRMPIYPKWMGADHADDL 459

  Fly   523 EYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGE----EWPNFSKEDPVYY----- 578
            :|.||:|....|.|||.:|.:.|.|::....||::|:|.....    .|..::.|:..|.
Mouse   460 QYVFGKPFATPLGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTHWYPYTLENGNYLDITKT 524

  Fly   579 IFSTDDKIEKLARGPLAARCSFWN---DYLPKVRSWAGTCDGDSGSASISP 626
            |.|...| |.|....|    .||.   :.||.|.....|.......:.::|
Mouse   525 ITSASMK-EHLREKFL----KFWAVTFEVLPTVTGDQDTLTPPEDDSEVAP 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	175/588 (30%)
Cel	NP_034015.1	COesterase	26..542	CDD:395084	174/585 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599		2/18 (11%)
		4 X 11 AA tandem repeats, O-glycosylated region	559..588		1/12 (8%)