Protein Alignment Ace and Bche

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_011238302.1
• Gene: Bche / 12038
• MGIID: 894278
• Length: 615
• Species: Mus musculus
• Alignment Length: 585
• Identity: 217/585 - (37%)
• Similarity: 315/585 - (53%)
• Gaps: 64/585 - (10%)

  Fly    44 VVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQER 108
            ::.|.:|.|||.|:.|.|..|..:.|||||:||:..|||:||.|...|..:.:||:.:.:|.|..
Mouse    46 IITTKTGRVRGLSMPVLGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDIHNATQYANSCYQNI 110

  Fly   109 YEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQ 173
            .:.||||.|.|:||||||:||||||:|||.|..                             .|:
Mouse   111 DQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVP-----------------------------KPK 146

  Fly   174 NTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAE 238
            |.|    :::|||||||.||:::|.:|:...:|.|..|||.|..|||||.|||.. |..|
Mouse   147 NAT----VMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAF-PGNP----- 201

  Fly   239 EAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSG 303
            :||||:||:||.||::|::.|..||||||:.:|:||||||::||:..|:.|.:..|..|.:::||
Mouse   202 DAPGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESG 266

  Fly   304 TMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTI-----SVQQWNSYS 363
            :.||||:....|:|......|.....|:    |.|...::.|:||.|.:.|     .|...:|
Mouse   267 SSNAPWAVKHPEEARNRTLTLAKFTGCS----KENEMEMIKCLRSKDPQEILRNERFVLPSDS-- 325

  Fly   364 GILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPR 428
             |||....||:||.||...|.||::...:|...||:|..:||||.||:|. ...|.||:.:.:.|
Mouse   326 -ILSINFGPTVDGDFLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYG-APGFSKDNDSLITR 388

  Fly   429 DKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQ-NQQQIGRAVGDHFFTCPTNEYAQALAER 492
            .::.|.:|..|...::..:||::|.|..|.|....: .:..:...:||:...||..|:.:..||.
Mouse   389 KEFQEGLNMYFPGVSRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTKKFAEL 453

  Fly   493 GASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKT 557
            ..:..:|:|.||:|...|.|||||:||.|||:.||.||...:.|...|....:.::.....|||.
Mouse   454 ENNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKTWANFAKY 518

  Fly   558 GNPAQDGEE-----WPNFSKEDPVYYIFSTD-DKIEKLARGPLAARCSFWNDYLPKVRSWAGTCD 616
            |:|  :|.:     ||.|:..:..|...:|: .||....|.|   :|.||..:.|||....|..|
Mouse   519 GHP--NGTQGNSTMWPVFTSTEQKYLTLNTEKSKIYSKLRAP---QCQFWRLFFPKVLEMTGDID 578

  Fly   617  616
            Mouse   579  578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	210/568 (37%)
Bche	XP_011238302.1	COesterase	46..563	CDD:365897	210/568 (37%)
		AChE_tetra	578..612	CDD:370053	1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847432
Domainoid	1	1.000	376	1.000	Domainoid score	I861
eggNOG	1	0.900	-	-		E2759_KOG4389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1985
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45275
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm42862
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	LDO	PTHR43918
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1321
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.760