Protein Alignment Ace and clt

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 158/608 - (25%)
• Similarity: 254/608 - (41%)
• Gaps: 113/608 - (18%)

  Fly    42 RLVVQTSSGPVRGR-SVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCV 105
            ::.|....|.:.|| ...|.|.|.:.:.|:|||:|||.:||||.|.|.|.:.      :....|.
  Fly    19 KVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQ------KQELDCS 77

  Fly   106 QE---RYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLI 167
            :|   .|:..| |:.|      ...|||||::||:||
  Fly    78 KEGNVSYQRDP-FTLE------VAGSEDCLFLNVYAP---------------------------- 107

  Fly   168 HNGNPQNTTNGLPILIWIYGGGFMTGSATLDI-YNADIMAAVGNVIVASFQYRVGAFGFLHLAPE 231
               ..::|...||:::||:||||..|:...|. :.|.:|..  .|||.:..||:||.|||.| ||
  Fly   108 ---KVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQ--EVIVVTLNYRLGALGFLSL-PE 166

  Fly   232 MPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVK 296
                  |...||:||.||.||:.|:::|..:|.|:|..:||||||||.|||:....:...:.|..
  Fly   167 ------EGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFH 225

  Fly   297 RGMMQSGTMNAPW-----SHMTSEKAVEI---------GKALINDCNCNASMLKTNPAHVMSCMR 347
            :.:|||||.|..|     :...:.:..|:         .|||:......    |..|..::
  Fly   226 KAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSE----KATPTAIL---- 282

  Fly   348 SVDAKTISVQQWNSYSGILSFPSAPTIDGA-----FLPADPMTLMKTAD-LKDYDILMGNVRDEG 406
               |.|:.|...:.....|.|...|.::.:     ||..|.|.||...| |....::||....||
  Fly   283 ---ANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEG 344

  Fly   407 TYFLL--YDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNP-GYQNQQQ 468
            ...::  ...::.::.|.|..:||:..|:      .:|.:|:..|...:...:.|.. ..:|...
  Fly   345 LAIVVKAKQKLEAYEDDLARLVPRNLVLD------PQAPEAQEAASDIRAFFFNGQALSKENMDN 403

  Fly   469 IGRAVGDHFFTCPTNEYAQ--ALAERGASVHYYYFTHRTSTSLW------GEWMGVLHGDEIEYF 525
            :.....|:.|:.......:  |..:..:.:::|...:....:|:      .:..||.|.|:|.|.
  Fly   404 LVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYL 468

  Fly   526 FGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKE---DPVYYIFSTDDKIE 587
            | |...:..:....:..:.:|:......||:.|.|:   ..|....|.   :|:.......|:..
  Fly   469 F-QMAGDETEMNRDDLMVTERLCEMWANFARDGKPS---PIWKPVKKPHNGEPIQLDCLLIDREL 529

  Fly   588 KLARGPLAARCSFWNDYLPKVRS 610
            |:...|...|..||.....:.||
  Fly   530 KMCSNPDGERMDFWRSMYRRYRS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	154/596 (26%)
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	154/594 (26%)