Protein Alignment Ace and Ces1d

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 169/610 - (27%)
• Similarity: 262/610 - (42%)
• Gaps: 129/610 - (21%)

  Fly    44 VVQTSSGPVRGRSVTVQG--REVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQ 106
            ||.|..|.|.|:.|.::|  :.|.|:.|||:||||:..|||..|.|||||:.|.:.|.....|.|
  Rat    25 VVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQ 89

  Fly   107 ERYEYFPGFSGEEIWNPNTN--------VSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADT 163
            :      ...|:.:....||        .||||||:||:.||
  Rat    90 D------AVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPA----------------------- 125

  Fly   164 DHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHL 228
             .|..|..       ||:::||:|||.:.|.|:  .|:..:::|..||:|.:.|||:|.:||.
  Rat   126 -DLTKNSR-------LPVMVWIHGGGLVVGGAS--TYDGQVLSAHENVVVVTIQYRLGIWGFF-- 178

  Fly   229 APEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRG 293
                 |...|.:.||.|..||..|:.|::||...|||||..:|:||||||..||:|.::||:.:.
  Rat   179 -----STGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLAKN 238

  Fly   294 LVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVM-SCMR--SVDAKTIS 355
            |..|.:.:||.:.......|..|.:....|.::.|       ||..:.|| .|:|  :.|....:
  Rat   239 LFHRAISESGVVLTSALITTDSKPIANLIATLSGC-------KTTTSAVMVHCLRQKTEDELLET 296

  Fly   356 VQQWNSYSGIL------SFPSAPT-IDGAFLPADPMTLMKTADLKDYDILMG-NVRDEGTYFLLY 412
            ..:.|.:...|      |:|..|| |||..||..|..::..........::| |.::.|  :::.
  Rat   297 SLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKTPEEILTEKSFNTVPYIVGINKQEFG--WIIP 359

  Fly   413 DFIDY------FDKDDATAL-----PRDKYLE-----IMNNIFGKATQAEREAIIFQYTSWEGNP 461
            ..:.|      .|:..|.:|     |..|..|     :....||......:...:||
  Rat   360 TLMGYPLSEGKLDQKTAKSLLWKSYPTLKISEKMIPVVAEKYFGGTDDPAKRKDLFQ-------- 416

  Fly   462 GYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTS-------TSLWGEWMGVLHG 519
                     ..|.|..|..|:...:::..:.||....|.|.:|.|       .::.|:     ||
  Rat   417 ---------DLVADVMFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGD-----HG 467

  Fly   520 DEIEYFFGQP-LNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDG-EEWPNFSKEDPVYYIFST 582
            ||:...||.| |.:.....  |..|.|.::.....||:.|:|...| ..||.:.:::....|.::
  Rat   468 DELFSVFGSPFLKDGASEE--ETNLSKMVMKYWANFARNGSPNGGGLPHWPEYDQKEGYLKIGAS 530

  Fly   583 DDKIEKLARGPLAARCSFWNDYLPK 607
            ....::|....:|    ||::...|
  Rat   531 TQAAQRLKDKEVA----FWSELRAK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	166/602 (28%)
Ces1d	NP_579829.3	COesterase	22..545	CDD:395084	166/602 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565