Protein Alignment Ace and nlgn4x

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 671
• Identity: 198/671 - (29%)
• Similarity: 304/671 - (45%)
• Gaps: 125/671 - (18%)

  Fly    13 MSLP-----LPLTIPLPLVLVLSLHLSGVCGVIDRL----------VVQTSSGPVRGR----SVT 58
            ||.|     |||......|||.|..|..:..:..|.          :|.|:.|.:||.    .:.
 Frog     1 MSRPNGLLWLPLIFTPVCVLVNSNLLLWIAALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIE 65

  Fly    59 VQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEE---- 119
            :.| .|..|.|:|||.||..:.||:.|.|...|.|:.:||:.:..|        |.|..|.
 Frog    66 ILG-PVEQYLGVPYASPPTGERRFQPPEPPSSWTGIKNATQFAPVC--------PQFLDERSLLN 121

  Fly   120 ----IW---NPNTNVS------EDCLYINVWAPAKARLRHGRGANGGEHPNGKQAD--------T 163
                ||   |.:|.||      |||||:|::.|.:      .||.     ..||||        .
 Frog   122 DMLPIWFTANLDTVVSYVQDQNEDCLYLNIYVPTE------DGAT-----TKKQADDIANNDRGE 175

  Fly   164 DHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHL 228
            |..||:.|     |..|::::|:||.:|.|  |.::.:..|:|:.|||||.:..||:|..|||
 Frog   176 DEDIHDPN-----NKKPVMVYIHGGSYMEG--TGNMIDGSILASHGNVIVITVNYRLGVLGFL-- 231

  Fly   229 APEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRG 293
                 |...:.|.||.||.||..|:||:::|..||||:|:.:|:||..||:|.|:...:|..:.|
 Frog   232 -----STGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG 291

  Fly   294 LVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQ 358
            |.::.::||||..:.|:  .:.:..:..:.|.:...|:  ||.|  ..::.|:|..:.|.:..|.
 Frog   292 LFQKAIIQSGTALSSWA--VNYQPAKYTRILADKVGCD--MLDT--IDLVECLRDKNYKELIQQS 350

  Fly   359 WNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFID-YFDKDD 422
            ....:..::|  .|.|||..:|.||..||:..:..:|||::|..:.||     ..|:| ..|.:|
 Frog   351 ITPATYHIAF--GPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG-----LKFVDGMVDNED 408

  Fly   423 ATALPRDKYLEIMN---NIFG--KATQAEREAIIFQYTSW--EGNPGYQNQQQIGRAVGDHFFTC 480
            ..:| .|....:.|   |::|  :.....||.|.|.||.|  :.||..:.:..:. ...||.:..
 Frog   409 GVSL-SDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVA-LFTDHQWVA 471

  Fly   481 PTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGK 545
            |....|...|..|:..::|.|.|...:.:...|....||||:.|.||.|:....:..........
 Frog   472 PAVATADLHARYGSPTYFYAFYHHCQSEMKPTWADSAHGDEVPYVFGIPMIGPTELFNCNFSKND 536

  Fly   546 RMLSAVI-----EFAKTGNP----AQDG----------EE--WPNFSKEDPVYYIFSTDDKIEKL 589
            .|||||:     .|||||:|    .||.          ||  |..:..:|.:|.......::...
 Frog   537 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKPNRFEEVAWSKYDPKDQLYLHIGLKPRVRDH 601

  Fly   590 ARGPLAARCSFWNDYLPKVRS 610
            .|   |.:.:||.:.:|.:.:
 Frog   602 YR---ATKVAFWLELVPHLHN 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	184/627 (29%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:365897	183/615 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910