Protein Alignment Ace and nlgn3

DIOPT Version :9

• Sequence 1: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 651
• Identity: 187/651 - (28%)
• Similarity: 287/651 - (44%)
• Gaps: 87/651 - (13%)

  Fly     9 RVLPMSLPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGR---EVHVYTGI 70
            :|.|..|.|.|.:......|||.|..     :....|.|..|.:||..|.:...   .|..|.|:
 Frog     7 KVAPRKLSLVLWVLSVTSRVLSSHAQ-----VYSQTVNTHYGKLRGTRVPLPSEILGPVDQYLGV 66

  Fly    71 PYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIW---NPNT------N 126
            |||.|||.:.||..|.|...|.|:.:||..|..|.|......|... ..:|   |.:|      .
 Frog    67 PYAAPPVGEKRFLPPEPPPSWSGIRNATHFSPVCPQNIQNAVPDIM-MPVWFTSNLDTVTGYLQE 130

  Fly   127 VSEDCLYINVWAPAKARLRHGRGA----------NGGEHPNGKQADTDHLIHNGNPQ----NTTN 177
            .||||||:|::.|.:...|..:..          .||  |:.|: ..:.|..|...:    ..|.
 Frog   131 QSEDCLYLNIYVPTEDVKRISKECVRKPNKKICRKGG--PSAKK-QGEELSDNDEDEEGDIRDTG 192

  Fly   178 GLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPG 242
            ..|::::|:||.:|.||.  ::.:..::|:.|||:|.:..||||..|||       |...:.|.|
 Frog   193 AKPVMVYIHGGSYMEGSG--NMIDGSVLASYGNVVVITLNYRVGVLGFL-------STGDQAAKG 248

  Fly   243 NVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNA 307
            |.||.||..|:||:.:|...|||:|..:|:||...|:|.|:...:|..:.||.:|.::|||:..:
 Frog   249 NYGLLDQIQALRWVSENVAFFGGDPHRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 313

  Fly   308 PWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAP 372
            .|:  .:.:.|:..:.|.....||  :|.|  ..::.|:|...||.:..|........::|  .|
 Frog   314 SWA--VNYQPVKYTRLLAEKVGCN--VLDT--VDMVDCLRQKSAKELVEQDIQPARYHVAF--GP 370

  Fly   373 TIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKY--LEIM 435
            .|||..:|.||..||:..:..:|||::|..:.||..|:    .:..|.:|..:.....|  ...:
 Frog   371 VIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFV----ENVVDAEDGVSGSDFDYSVSNFV 431

  Fly   436 NNIFG--KATQAEREAIIFQYTSW--EGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASV 496
            :|::|  :.....||.|.|.||.|  ..||..:.:..:. ...||.:..|:...|...|..|:..
 Frog   432 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVA-LFTDHQWVEPSVVTADLHARYGSPT 495

  Fly   497 HYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVI-----EFAK 556
            ::|.|.|...:.:...|....||||:.|.||.|:.......|........|||||:     .|||
 Frog   496 YFYAFYHHCQSLMKPAWADAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAK 560

  Fly   557 TGNP--------------AQDGEE--WPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYL 605
            ||:|              |...||  |..::..|.:|.......::....|   |.:.:||...:
 Frog   561 TGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYR---ATKVAFWKHLV 622

  Fly   606 P 606
            |
 Frog   623 P 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	175/612 (29%)
nlgn3	XP_012823589.1	COesterase	31..618	CDD:278561	175/620 (28%)
		Aes	<195..>302	CDD:223730	44/115 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910