Protein Alignment Ace and ces2

DIOPT Version :10

• Sequence 1: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 643
• Identity: 186/643 - (28%)
• Similarity: 282/643 - (43%)
• Gaps: 170/643 - (26%)

  Fly    26 VLVLSLHLSGVCGVID-RLVVQTSSGPVRGRSVTVQ--GREVHVYTGIPYAKPPVEDLRFRKPVP 87
            ||:|......:.|..| |.::.|..|.:.|::|..:  .|.|||:.|:|:||||:..|||..|.|
 Frog     7 VLLLCCATLEIYGTEDARPLLMTKYGQLLGKTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQP 71

  Fly    88 AEPWHGVLDATRLSATCVQER------YEYFPG---FSGEEIWNPNTNVSEDCLYINVWAPAKAR 143
            .|||..|.:||..|..|:|::      .::|..   ||         .|||||||:||:.|
 Frog    72 PEPWSSVREATAPSPMCLQDKEVMELLADFFKAKFDFS---------RVSEDCLYLNVFTP---- 123

  Fly   144 LRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAV 208
                  |:.||:|                     |||::::|:|||...|.|::  :....::|.
 Frog   124 ------ADKGENP---------------------GLPVMVFIHGGGLAIGGASM--FEGSALSAY 159

  Fly   209 GNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLF 273
            .||:|.|.|||:|..|||       |...:|..||.|..||..|::|::||...|||:|:.:|:|
 Frog   160 ENVVVVSIQYRLGIMGFL-------STGDKEVRGNFGFLDQVAALQWVRDNIKDFGGDPQSVTIF 217

  Fly   274 GESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKAL---INDCNCNASML 335
            |||||..||:|.::||::.||..|.:.:||....|  .:|:.|..||...|   ||..:|:.|.|
 Frog   218 GESAGGLSVSALVLSPLSEGLFHRAIAESGVAILP--GLTASKTEEILPLLDMVINVSSCSVSDL 280

  Fly   336 KTNPAHVMSCMRS-VDAKTISVQQWNSYSGILSFPSAPTIDGAFLPAD----------------- 382
                   :.|::: .:.:.|.:.....|   :.||:  .:||.|||..
 Frog   281 -------VGCLKNKTEDEIIEITAAMRY---VIFPA--VVDGVFLPKPAEEILAAKESHPVPFLI 333

  Fly   383 -----------PMTLMKTA-----DLKDYDILMGNVRDEGTYFLLYDFI--DYF-DKDDATALPR 428
                       |:||..|.     :.||...::|.:....|...:..||  :|| |.:|    |:
 Frog   334 GINNHEFGSMLPVTLNITGYREGMEKKDIQAILGALPLLNTVSSVIPFIMEEYFGDTND----PK 394

  Fly   429 DKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERG 493
                |:.||....|                               ||..|..|....|:...:.|
 Frog   395 ----ELRNNFLDLA-------------------------------GDIIFVIPALRTAKYHRDSG 424

  Fly   494 ASVHYYYFTHRTSTSLWG----EWMGVLHGDEIEYFFGQP-LNNSLQYR----PVERELGKRMLS 549
            ..|::|.|.||  .||:.    :::...||||:.:..|.| |.|.:.::    ..|:.|.|.::.
 Frog   425 FPVYFYEFQHR--PSLYADSKEDFVKADHGDELYFVGGGPFLKNGILFKSNGTEEEKILSKTIMK 487

  Fly   550 AVIEFAKTGNPAQDG-EEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLP 606
            ....||:.|:|...| .|||.:. ||..|...:...|..:..:|   .|..||...||
 Frog   488 YWANFARNGDPNGHGLAEWPKYD-EDEDYLEINLTQKSSQRLKG---ERFEFWTITLP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ace	NP_476953.1	COesterase	43..601	CDD:395084	176/618 (28%)
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	176/618 (28%)