DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and PRY3

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_012457.1	Gene:	PRY3 / 853367	SGDID:	S000003614	Length:	881	Species:	Saccharomyces cerevisiae

Alignment Length:	314	Identity:	81/314 - (25%)
Similarity:	136/314 - (43%)	Gaps:	61/314 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSAVLLTTIMIISCEVAFACNGKIIASGITAEERSIILQEHNRLRQI-VATGRYPGQPGAENMRE 67
            |.:|||..::.:..:..|            ....|.:|.|||:.|.: |.|.            .
Yeast     5 PISVLLGCLVAVKAQTTF------------PNFESDVLNEHNKFRALHVDTA------------P 45

  Fly    68 IVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQ 132
            :.|.|.||..||.:||  |:......|.:....|:|||:.::      |.|    .:.:|:.|:.
Yeast    46 LTWSDTLATYAQNYAD--QYDCSGVLTHSDGPYGENLALGYT------DTG----AVDAWYGEIS 98

  Fly   133 KYSFGD-AWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLYVCNYGPGGNVVGYNPYEVGKP 196
            ||::.: .:|..|||::|:||..|:.:|||| :|..|: :|...||:|.|.||.:|....|| :|
Yeast    99 KYNYSNPGFSESTGHFTQVVWKSTAEIGCGY-KYCGTT-WNNYIVCSYNPPGNYLGEFAEEV-EP 160

  Fly   197 SCSTYGMKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQF 261
            ..||.....||     .::..::....|...::.:.....||.::.||..::::..:..||
Yeast   161 LISTVSSSSSS-----SSSTSTTSDTVSTISSSIMPAVAQGYTTTVSSAASSSSLKSTTIN---- 216

  Fly   262 SYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGSASRGG-SHAYTTDPS 314
                  |....|:..:.|    .....|..:.|.|:..|||... :.:|.|..|
Yeast   217 ------PAKTATLTASSS----TVITSSTESVGSSTVSSASSSSVTTSYATSSS 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	45/144 (31%)
PRY3	NP_012457.1	CAP_PRY1-like	24..152	CDD:349403	49/153 (32%)
PRY3	NP_012457.1	ser_rich_anae_1	<598..>855	CDD:411418
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740