DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and Crispld1

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001343480.1	Gene:	Crispld1 / 83691	MGIID:	1934666	Length:	500	Species:	Mus musculus

Alignment Length:	257	Identity:	72/257 - (28%)
Similarity:	115/257 - (44%)	Gaps:	54/257 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTIN 96
            ||..:...||..||:||..|       .|.|.||..:.||.||...|:.||:.|.:.|.|...:.
Mouse    57 ITDNDMQSILDLHNKLRSQV-------YPTASNMEYMTWDVELERSAESWAEMCLWEHGPASLLP 114

  Fly    97 RFTMGQNLAIIWSTAPLDADDGDF--PS-RIQSWFNEVQKYSFG-----DAW------SPKTGHY 147
              ::||||...|         |.:  |: .:|:|::||:.:|:.     |.:      .|...||
Mouse   115 --SIGQNLGAHW---------GRYRPPTFHVQAWYDEVRDFSYPYENECDPYCPFRCSGPVCTHY 168

  Fly   148 SQLVWGETSLVGCGYAEYKDTSKYNKLY------VCNYGPGGNVVGYNPYEVGKPSCS----TYG 202
            :|:||..:|.:||......:.:.:.:::      ||||.|.||..|:.||:.|:| ||    ::|
Mouse   169 TQVVWATSSRIGCAVNLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGRP-CSACPPSFG 232

  Fly   203 MKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSS----PSSQTANNNPPTNNINKSQ 260
               ....:.||...||    :..|.....||.|.....|    ...:|.:::...|::..:|
Mouse   233 ---GGCRENLCYKEGS----DRYYTPREEETNEIERQQSQVHDTHVRTRSDDSDRNDVISTQ 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	46/162 (28%)
Crispld1	NP_001343480.1	CAP_CRISPLD1	62..207	CDD:349407	46/162 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..281		3/22 (14%)
		LCCL	291..375	CDD:128866
		LCCL	394..492	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841166
Domainoid	1	1.000	72	1.000	Domainoid score	I9265
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43032
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750