Protein Alignment CG8483 and CRISPLD1

DIOPT Version :10

• Sequence 1: NP_650264.1
• Gene: CG8483 / 41623
• FlyBaseID: FBgn0038126
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_113649.1
• Gene: CRISPLD1 / 83690
• HGNCID: 18206
• Length: 500
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 80/294 - (27%)
• Similarity: 128/294 - (43%)
• Gaps: 64/294 - (21%)

  Fly     1 MMQPSAVLLTTIMIISCEVAFACNGK-IIAS-----GITAEERSIILQEHNRLRQIVATGRYPGQ 59
            |:.|:|.||..::    |.....:|: .||.     .||..:...||..||:||..|       .
Human    24 MVVPNATLLEKLL----EKYMDEDGEWWIAKQRGKRAITDNDMQSILDLHNKLRSQV-------Y 77

  Fly    60 PGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLDADDGDF--PS 122
            |.|.||..:.||.||...|:.||::|.:.|.|...:.  ::||||...|         |.:  |:
Human    78 PTASNMEYMTWDVELERSAESWAESCLWEHGPASLLP--SIGQNLGAHW---------GRYRPPT 131

  Fly   123 -RIQSWFNEVQKYSFG-----------DAWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLY 175
             .:|||::||:.:|:.           ....|...||:|:||..::.:||......:.:.:.:::
Human   132 FHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVVWATSNRIGCAINLCHNMNIWGQIW 196

  Fly   176 ------VCNYGPGGNVVGYNPYEVGKPSCS----TYGMKPSSRYQGLCAAPGSSPAANSVYGANT 230
                  ||||.|.||..|:.||:.|:| ||    ::|   ....:.||...||    :..|....
Human   197 PKAVYLVCNYSPKGNWWGHAPYKHGRP-CSACPPSFG---GGCRENLCYKEGS----DRYYPPRE 253

  Fly   231 IETYEYGYNSS----PSSQTANNNPPTNNINKSQ 260
            .||.|.....|    ...:|.:::...|.:..:|
Human   254 EETNEIERQQSQVHDTHVRTRSDDSSRNEVISAQ 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	CAP_euk	37..180	CDD:349399	45/162 (28%)
CRISPLD1	NP_113649.1	CAP_CRISPLD1	62..207	CDD:349407	45/162 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..281		5/26 (19%)
		LCCL	291..375	CDD:128866
		LCCL	394..491	CDD:427521