DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and CLEC18B

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001011880.2	Gene:	CLEC18B / 497190	HGNCID:	33849	Length:	455	Species:	Homo sapiens

Alignment Length:	202	Identity:	65/202 - (32%)
Similarity:	90/202 - (44%)	Gaps:	25/202 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IASGITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPH 92
            :|..:..:|..::|..|||||..|       ||.|.:||.:.|.|.||..||..|..|..   |.
Human    39 MAGALNRKESFLLLSLHNRLRSWV-------QPPAADMRRLDWSDSLAQLAQARAALCGI---PT 93

  Fly    93 RTINRFTMGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQKYSF--GD-AWSPKTGHYSQLVWGE 154
            .:: ...:.:.|.:.|:...|.|....|...:..||.|.|:||.  |: |.:....||:||||..
Human    94 PSL-ASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWAT 157

  Fly   155 TSLVGCGYAEYKDTSKYNKLYVCNYGPGGN--VVGYN--PYEVGKPSCSTYGMKPSSRYQ----- 210
            :|.:|||...........:.:||.|.||||  |.|..  ||:.| ..||......|..::
Human   158 SSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNGKTIIPYKKG-AWCSLCTASVSGCFKAWDHA 221

  Fly   211 -GLCAAP 216
             |||..|
Human   222 GGLCEVP 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	46/145 (32%)
CLEC18B	NP_001011880.2	SCP_euk	50..183	CDD:240180	46/143 (32%)
CLEC18B	NP_001011880.2	CLECT	310..443	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151025
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7576
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750