DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and crispld1b

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_009296842.1	Gene:	crispld1b / 393442	ZFINID:	ZDB-GENE-040426-1204	Length:	509	Species:	Danio rerio

Alignment Length:	337	Identity:	92/337 - (27%)
Similarity:	134/337 - (39%)	Gaps:	105/337 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLLTTIM-IISCEVAFACNGKIIAS------------------GITAEERSIILQEHNRLRQIVA 52
            |||.|:. ::|..:..|.:.:.|..                  .|:..:..:||..||:||
Zfish    14 VLLVTVQTVVSMVIPNATHLEAILEKYMDKDETWWQSKSRGKRAISQSDMQLILDLHNKLR---- 74

  Fly    53 TGRYPGQ--PGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLDA 115
                 ||  |.|.||..:|||.||...|:.||..|.:.|.|...:.|  :||||...|..
Zfish    75 -----GQVYPPASNMEYMVWDTELERSAEHWAHTCLWEHGPSHLLTR--IGQNLGAHWGR----- 127

  Fly   116 DDGDFPS--RIQSWFNEVQKYSFG-----------DAWSPKTGHYSQLVWGETSLVGCGYAEYKD 167
               |.|.  .:|:|::||:.:|:.           ....|...||:||||..::.:||......:
Zfish   128 ---DRPPTFHVQAWYDEVRDFSYPYPQECNPHCPYRCSGPVCTHYTQLVWATSNKIGCAINVCYN 189

  Fly   168 TSKYNKLY------VCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAPGSSPAANSVY 226
            .:.:..::      ||||.|.||..|:.||:.|.| ||  ...||  |.|.|       ..|..|
Zfish   190 MNVWGMIWAKAVYLVCNYSPPGNWWGHAPYKHGTP-CS--ACPPS--YGGGC-------RNNLCY 242

  Fly   227 ---GANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSYNQPRPKPV---------QTINPNPS 279
               |:|    |.|      :.:|..||            |.:|.|:||         :|..|:|:
Zfish   243 KDDGSN----YHY------TPETEENN------------YIEPEPEPVRSHDTHYRDETTTPSPN 285

  Fly   280 PFNPQAAVPSAS 291
            ....:..|.|.|
Zfish   286 ENIERNEVSSTS 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	48/163 (29%)
crispld1b	XP_009296842.1	SCP_euk	64..208	CDD:240180	48/162 (30%)
		LCCL	301..385	CDD:128866
		LCCL	404..501	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585648
Domainoid	1	1.000	81	1.000	Domainoid score	I8420
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25860
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6223
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.780