DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and CLEC18A

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_016878695.1	Gene:	CLEC18A / 348174	HGNCID:	30388	Length:	476	Species:	Homo sapiens

Alignment Length:	202	Identity:	64/202 - (31%)
Similarity:	89/202 - (44%)	Gaps:	25/202 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IASGITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPH 92
            :|..:..:|..::|..|||||..|       ||.|.:||.:.|.|.||..||..|..|   ..|.
Human    39 MAGALNRKESFLLLSLHNRLRSWV-------QPPAADMRRLDWSDSLAQLAQARAALC---GTPT 93

  Fly    93 RTINRFTMGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQKYSF--GD-AWSPKTGHYSQLVWGE 154
            .:: ...:.:.|.:.|:...|.|....|...:..||.|.|:||.  |: |.:....||:||||..
Human    94 PSL-ASGLWRTLQVGWNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWAT 157

  Fly   155 TSLVGCGYAEYKDTSKYNKLYVCNYGPGGN--VVGYN--PYEVGKPSCSTYGMKPSSRYQ----- 210
            :|.:|||...........:.:||.|.|.||  |.|..  ||:.| ..||......|..::
Human   158 SSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKG-AWCSLCTASVSGCFKAWDHA 221

  Fly   211 -GLCAAP 216
             |||..|
Human   222 GGLCEVP 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	46/145 (32%)
CLEC18A	XP_016878695.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151027
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7576
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750