DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and scl-10

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_502498.1	Gene:	scl-10 / 186049	WormBaseID:	WBGene00009891	Length:	212	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	66/228 - (28%)
Similarity:	109/228 - (47%)	Gaps:	46/228 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LTTIMIIS-CEV--AFACNGKIIASGITAEERSIILQEHNRLRQIVATGRYPG----QPGAENMR 66
            |..::|.| ||.  .|:..||           :.||..||.||..:|.|:|..    :|.|.||.
Worm     7 LICLLIFSFCETLCEFSETGK-----------NYILSRHNYLRSQIALGKYVAGNSTKPSASNMM 60

  Fly    67 EIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPL----DAD-DGDFPSRIQS 126
            :::||..|...||.::..|...|    :.:|..:|:|:  .|.|:|:    ||: .|:..:.:
Worm    61 KLIWDTTLETTAQDYSTGCPTGH----SASRANIGENM--YWWTSPVVTQTDAELLGNRSANL-- 117

  Fly   127 WFNEVQKYSFG------DAWSPKTGHYSQLVWGETSLVGCGYAEYKDTS---KYNKLYVCNYGPG 182
            |.:|.|::.:.      :.::...||.:|:.|..|:.:|||.::....|   :|  :.||.|.|.
Worm   118 WESEFQRFGWNGNLLTEELFNSGIGHATQMAWATTNKIGCGISKCSSDSFGTQY--VVVCLYSPA 180

  Fly   183 GNVVGYNPYEVGKPSCSTY--GMKPSSRYQGLC 213
            ||.:|.:.|:.|: :||..  |....|. .|||
Worm   181 GNYIGMDIYKSGE-TCSNCPDGTNCESS-TGLC 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	44/160 (28%)
scl-10	NP_502498.1	SCP	25..179	CDD:214553	47/174 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161834
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	1	1.000	-	-		FOG0000604
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100188
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.650