DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and Crispld2

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_612527.2	Gene:	Crispld2 / 171547	RGDID:	620860	Length:	497	Species:	Rattus norvegicus

Alignment Length:	386	Identity:	108/386 - (27%)
Similarity:	151/386 - (39%)	Gaps:	116/386 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IASGITAEERSIILQEHNRLRQIVATGRYPGQ--PGAENMREIVWDDELAARAQKWADNCQFRHD 90
            :...|...:|..||..||:||         ||  |.|.||..:.||:||...|..||..|.:.|.
  Rat    47 VRRAIPMSDRQEILMLHNKLR---------GQVYPPASNMEYMTWDEELERSAAAWAQRCLWEHG 102

  Fly    91 PHRTINRFTMGQNLAIIWSTAPLDADDGDFPS---RIQSWFNEVQKYSFG-----DAWSPK--TG 145
            |...:  .::|||||:.|         |.:.|   .:|||::||:.|::.     :.|.|:  :|
  Rat   103 PASLL--VSIGQNLAVHW---------GRYRSPGFHVQSWYDEVKDYTYPYPHECNPWCPERCSG 156

  Fly   146 ----HYSQLVWGETSLVGCGYAEYKDTSKY-----NKLY-VCNYGPGGNVVGYNPYEVGKPSCST 200
                ||:|:||..|:.:||.....:..|.:     |.:| ||||.|.||.:|..||:.|:| ||.
  Rat   157 AMCTHYTQMVWATTNKIGCAVHTCRSMSVWGDIWENAVYLVCNYSPKGNWIGEAPYKHGRP-CSE 220

  Fly   201 YGMKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTAN--NNPPTNNINKSQFSY 263
            .   ||| |.|.|              .|.:...|..|:..|.....|  .:||.   .:....:
  Rat   221 C---PSS-YGGGC--------------RNNLCYREEHYHQKPEVDEMNEVESPPA---PEETHVW 264

  Fly   264 NQPR-PKPVQTINPNPSPFNPQAA-------------------VPS------ASTFGGSSFGSAS 302
            .||| .||.:|.......|..|..                   .|:      |..||...:.|:|
  Rat   265 VQPRVVKPSKTKKTPVVNFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLNNKAKVFGSLFYESSS 329

  Fly   303 --------------RGGSHAYTTD-------PSQSAGRYKHKLEAYRPSAAEFEKSVHKHT 342
                          |||....|.:       .||..|  ...|..|:||:: |..|..|.|
  Rat   330 SICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNG--LESLSKYKPSSS-FTVSKVKET 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	54/164 (33%)
Crispld2	NP_612527.2	SCP_euk	56..201	CDD:240180	54/164 (33%)
		LCCL	286..370	CDD:128866	14/85 (16%)
		LCCL	389..487	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750