DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8483 and crispld2

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_003199065.1	Gene:	crispld2 / 100535149	ZFINID:	ZDB-GENE-130131-1	Length:	508	Species:	Danio rerio

Alignment Length:	282	Identity:	93/282 - (32%)
Similarity:	128/282 - (45%)	Gaps:	80/282 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTM 100
            :|..||:.||:||..|       .|.|.||..::|||||...|..||:.||:.|.|...:  .::
Zfish    60 DREEILKLHNKLRGEV-------YPTASNMEYMIWDDELERSATSWAEQCQWEHGPQDLL--MSI 115

  Fly   101 GQNLAIIWSTAPLDADDGDFPS---RIQSWFNEVQKYSFG-----DAWSPK--TG----HYSQLV 151
            |||||:.|         |.:.|   .:|:|::||:.|::.     :.|.|:  :|    ||:|||
Zfish   116 GQNLAVHW---------GRYRSPAYHVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLV 171

  Fly   152 WGETSLVGCG---------YAEYKDTSKYNKLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSS 207
            |..|:.|||.         :.|..:.:.|   .||||.|.||.:|..||:.|:| ||.  ..||
Zfish   172 WATTNRVGCAVHVCPRMNVWGEIWENAVY---LVCNYSPKGNWIGEAPYQHGRP-CSQ--CPPS- 229

  Fly   208 RYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSYNQPR---PK 269
             |.|:|       ..|..|..:: |..|              .|..|.:.|.|... |||   ||
Zfish   230 -YGGVC-------RDNLCYKRDS-ERQE--------------TPEMNEVEKPQEPL-QPRTTPPK 270

  Fly   270 PVQTINPNP-SPFNPQAAVPSA 290
            |    .|.| ||..|..|.||:
Zfish   271 P----QPKPSSPKKPANAKPSS 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	55/165 (33%)
crispld2	XP_003199065.1	SCP_euk	61..206	CDD:240180	55/165 (33%)
		LCCL	299..382	CDD:128866
		LCCL	402..495	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585658
Domainoid	1	1.000	81	1.000	Domainoid score	I8420
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25860
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750