DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8483 and crispld1

DIOPT Version :9

Sequence 1:	NP_650264.1	Gene:	CG8483 / 41623	FlyBaseID:	FBgn0038126	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002937123.2	Gene:	crispld1 / 100490431	XenbaseID:	XB-GENE-989389	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	80/262 - (30%)
Similarity:	114/262 - (43%)	Gaps:	51/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTIN 96
            ||..:..:||..||:||..|       .|.|.||..::||.||...|:.||:.|.:.|.|...:.
Frog    57 ITESDMKLILDLHNKLRGEV-------YPPASNMEFMIWDVELERSAEAWAETCLWEHGPADLLP 114

  Fly    97 RFTMGQNLAIIWSTAPLDADDGDF--PS-RIQSWFNEVQKYSFG-----DAW------SPKTGHY 147
              .:||||...|         |.:  |: .:|:|::||:.|:|.     |.:      .|...||
Frog   115 --VIGQNLGAHW---------GRYRPPTYHVQAWYDEVRDYTFPYPQECDPYCPFRCSGPVCTHY 168

  Fly   148 SQLVWGETSLVGCGYAEYKDTSKYNKLY------VCNYGPGGNVVGYNPYEVGKPSCSTYGMKPS 206
            :||||..:|.:||......:.:.:.:::      ||||.|.||..|:.||:.|.| ||  ...||
Frog   169 TQLVWATSSRIGCAINLCHNMNVWGQIWPKAIYLVCNYSPKGNWWGHAPYKHGHP-CS--ACPPS 230

  Fly   207 SRYQG-----LCAAPGSS---PAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSY 263
              |.|     ||...||.   |........|.||........:.|...|..|.||::.....|..
Frog   231 --YGGGCKDNLCYKDGSDLHYPLPEPEEETNEIEGQSSKVLDTTSQSRARTNSPTSSTRVESFDN 293

  Fly   264 NQ 265
            |:
Frog   294 NE 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8483	NP_650264.1	SCP_euk	37..180	CDD:240180	48/162 (30%)
crispld1	XP_002937123.2	CAP_CRISPLD1	62..207	CDD:349407	48/162 (30%)
		LCCL	304..388	CDD:128866
		LCCL	407..506	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	78	1.000	Domainoid score	I8613
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6223
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950