DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8141 and Rnf185

DIOPT Version :9

Sequence 1:	NP_731776.1	Gene:	CG8141 / 41622	FlyBaseID:	FBgn0038125	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_663330.2	Gene:	Rnf185 / 193670	MGIID:	1922078	Length:	228	Species:	Mus musculus

Alignment Length:	222	Identity:	54/222 - (24%)
Similarity:	82/222 - (36%)	Gaps:	45/222 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QGEVISKGYIPDLSNANVN-------QQQQQENDGEDDLLPGTRLRYRRRNLHLDPYVCNECNQY 91
            |..:.|||.....|..|.|       .....|:.|:|                 ..:.||.|...
Mouse    34 QAAMASKGPSASASTENSNAGGPSGSSNGTGESGGQD-----------------STFECNICLDT 81

  Fly    92 VRGGVITICGHLFCWTCL--WPKLSGTAQPRCPCCQRHLLMYEDIMPFHGEGPNARQE--DNNVP 152
            .:..||::|||||||.||  |.:.....|. ||.|:.. :..:.::|.:|.|...:|:  :...|
Mouse    82 AKDAVISLCGHLFCWPCLHQWLETRPNRQV-CPVCKAG-ISRDKVIPLYGRGSTGQQDPREKTPP 144

  Fly   153 AQPGSVPRP------TGLYLSDTDFPCWFAVNDPVDGCPATFPDIRRERDLHCAIRLIPMVYPWI 211
            ...|..|.|      .|....|..|...|.:.....|..||..:|...|....    :|....::
Mouse   145 RPQGQRPEPENRGGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPA----VPGTPQYV 205

  Fly   212 GAQ-ISFLKWFQLGCVLLIFLIWSVLS 237
            ..| :|.|..|    |.|:.:.|.:::
Mouse   206 DEQFLSRLFLF----VALVIMFWLLIA 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8141	NP_731776.1	zf-C3HC4_2	85..124	CDD:290634	18/40 (45%)
Rnf185	NP_663330.2	RING	74..119	CDD:238093	19/46 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000717
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12313
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870