DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 2mit and RLP15

DIOPT Version :9

Sequence 1:	NP_001262529.1	Gene:	2mit / 41616	FlyBaseID:	FBgn0260793	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_177559.1	Gene:	RLP15 / 843759	AraportID:	AT1G74190	Length:	965	Species:	Arabidopsis thaliana

Alignment Length:	432	Identity:	110/432 - (25%)
Similarity:	172/432 - (39%)	Gaps:	108/432 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SYQSIHRMLRDENEPDSFRGELRYQQKRHKRELELNAPANKLNLTHRDLRTFNS-----TGGQWK 117
            |.||:..:...:|:   |.|...:           .:.||..||....|.:.:|     :...||
plant   290 SLQSLEYLSLFDND---FEGSFSF-----------GSLANLSNLMVLKLCSKSSSLQVLSESSWK 340

  Fly   118 GDFQV----------------------ITAMDLSSN----QLESLSLDNFNQLRQLDLGNNSLEV 156
            ..||:                      :..:|||.|    :|.|..|.|..:|:.|.|.||..
plant   341 PKFQLSVIALRSCNMEKVPHFLLHQKDLRHVDLSDNNISGKLPSWLLANNTKLKVLLLQNNLF-- 403

  Fly   157 IPLSLADTNMSLP-----FVTLDLSCNKFSQISTSFFAQRLPQLKNLNLAHNELLNISRESFYNL 216
                   |:..:|     .:.||:|.|.|:.:.........|.|:.||.:.|........|..|:
plant   404 -------TSFQIPKSAHNLLFLDVSANDFNHLFPENIGWIFPHLRYLNTSKNNFQENLPSSLGNM 461

  Fly   217 LELQTLVLSHNNISDIDYETFL-ALPNLQYLDLSHNRLSGSAIRALQGIPDLVSLSIAYNPDVGV 280
            ..:|.:.||.|:.......:|: ...::..|.||||:|||..........:::.|.:..|...|.
plant   462 NGIQYMDLSRNSFHGNLPRSFVNGCYSMAILKLSHNKLSGEIFPESTNFTNILGLFMDNNLFTGK 526

  Fly   281 AMQEFVASWSLKELDASGTGLCQV-PAALAQ--SVRTLKLSDNWLKAINCGDMDSYPL------- 335
            ..|...:..:|:.||.|...|..| |:.:.:  |:..|.:|||:||    ||:   |:
plant   527 IGQGLRSLINLELLDMSNNNLTGVIPSWIGELPSLTALLISDNFLK----GDI---PMSLFNKSS 584

  Fly   336 LQYLDLSHSRIAQV----EDDALGRLELLESLFLDRNLLMRVPSSLPPSLEHLFLQHNQIM-ELP 395
            ||.||||.:.::.|    .|...|.:.||:    |..|...:|.:|..::|.|.|::|:.. ::|
plant   585 LQLLDLSANSLSGVIPPQHDSRNGVVLLLQ----DNKLSGTIPDTLLANVEILDLRNNRFSGKIP 645

  Fly   396 ----------------------PQAFVGLVNLQTLDLSNNRL 415
                                  |....||.|:|.||||||||
plant   646 EFINIQNISILLLRGNNFTGQIPHQLCGLSNIQLLDLSNNRL 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
2mit	NP_001262529.1	LRR_RI	124..355	CDD:238064	69/254 (27%)
		leucine-rich repeat	124..143	CDD:275380	8/22 (36%)
		leucine-rich repeat	144..167	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..194	CDD:275380	5/21 (24%)
		LRR_8	193..253	CDD:290566	17/60 (28%)
		leucine-rich repeat	195..218	CDD:275380	6/22 (27%)
		leucine-rich repeat	219..242	CDD:275380	5/23 (22%)
		LRR_8	241..301	CDD:290566	16/59 (27%)
		leucine-rich repeat	243..311	CDD:275380	19/70 (27%)
		leucine-rich repeat	312..335	CDD:275380	8/22 (36%)
		LRR_8	334..415	CDD:290566	32/114 (28%)
		leucine-rich repeat	336..359	CDD:275380	9/26 (35%)
		leucine-rich repeat	360..380	CDD:275380	5/19 (26%)
		LRR_8	379..460	CDD:290566	18/60 (30%)
		LRR_4	379..>415	CDD:289563	16/58 (28%)
		leucine-rich repeat	381..404	CDD:275380	8/45 (18%)
		leucine-rich repeat	405..449	CDD:275380	9/11 (82%)
RLP15	NP_177559.1	LRRNT_2	28..72	CDD:369783
		PLN00113	<105..>287	CDD:215061
		leucine-rich repeat	106..133	CDD:275380
		leucine-rich repeat	134..157	CDD:275380
		leucine-rich repeat	158..182	CDD:275380
		leucine-rich repeat	183..207	CDD:275380
		leucine-rich repeat	208..245	CDD:275380
		leucine-rich repeat	246..269	CDD:275380
		PLN00113	249..>892	CDD:215061	110/432 (25%)
		leucine-rich repeat	270..293	CDD:275380	1/2 (50%)
		leucine-rich repeat	294..318	CDD:275380	5/37 (14%)
		leucine-rich repeat	319..357	CDD:275380	7/37 (19%)
		leucine-rich repeat	368..392	CDD:275380	8/23 (35%)
		leucine-rich repeat	440..463	CDD:275380	6/22 (27%)
		leucine-rich repeat	465..488	CDD:275380	5/22 (23%)
		leucine-rich repeat	489..512	CDD:275380	8/22 (36%)
		leucine-rich repeat	513..536	CDD:275380	4/22 (18%)
		leucine-rich repeat	537..560	CDD:275380	7/22 (32%)
		leucine-rich repeat	561..584	CDD:275380	9/29 (31%)
		leucine-rich repeat	585..607	CDD:275380	8/21 (38%)
		leucine-rich repeat	608..629	CDD:275380	7/24 (29%)
		leucine-rich repeat	630..652	CDD:275380	5/21 (24%)
		leucine-rich repeat	653..676	CDD:275380	3/22 (14%)
		leucine-rich repeat	677..697	CDD:275380	9/11 (82%)
		leucine-rich repeat	744..804	CDD:275380
		leucine-rich repeat	749..780	CDD:275380
		leucine-rich repeat	805..828	CDD:275380
		leucine-rich repeat	829..850	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000