DRSC/TRiP Functional Genomics Resources

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Protein Alignment 2mit and chadla

DIOPT Version :9

Sequence 1:NP_001262529.1 Gene:2mit / 41616 FlyBaseID:FBgn0260793 Length:1155 Species:Drosophila melanogaster
Sequence 2:XP_017210255.1 Gene:chadla / 565474 ZFINID:ZDB-GENE-121205-4 Length:791 Species:Danio rerio


Alignment Length:722 Identity:153/722 - (21%)
Similarity:237/722 - (32%) Gaps:262/722 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 QKRHKRELELNAPANKLNLTHRDLRTFNSTG---GQWKGDFQVITAMDLSSNQLESL---SLDNF 141
            :|.:..||..||..:...||...|:..:...   |.::| ...:..:||::|.::.|   |.|..
Zfish    59 KKNNFGELPKNAFKHTPYLTQLSLQGCSVQAVREGAFRG-LSRLLQLDLTNNNIDILYQESFDGL 122

  Fly   142 NQLRQLDLGNNSLEVI-PLSLADTN----MSLPF-----------------VTLDLSCNKFSQIS 184
            :.|:||.|..|.:|.| |.:.|..|    :||.:                 ..|.||.|..:.::
Zfish   123 SSLKQLYLDRNRIEEIHPGAFAALNSLNLLSLTYNQLVYLPNMAFQGMMNIQMLHLSHNSLNNLA 187

  Fly   185 TSFFAQRLPQLKNLNLAHNELLNISRESFYNLLE-----------------------LQTLVLSH 226
            |..||..| .|.:|||.||||.....::...|:|                       |..|.|.|
Zfish   188 TEAFAGLL-ALTHLNLDHNELQYFPTKTMTRLIEVTHLDMSYNPMTYLVEESVVMPKLTHLSLKH 251

  Fly   227 NNISDIDYETFLALPNLQYLDLSHNRLSGSAIRALQGIPDLVSLSIAYNPDVGVAMQEFVASWSL 291
            |.:.|:...|....|.:.:||||.|:|  |.|:||.....|.||::..||.....:...:..|:|
Zfish   252 NALQDLSESTISLSPVISHLDLSFNQL--SYIQALAASTHLTSLNLTGNPIRCTCLLRDLKLWAL 314

  Fly   292 KELDASGT---GLCQVPAAL--------------------------------------------A 309
            |    ||.   |:|..|..|                                            |
Zfish   315 K----SGIRLFGVCAWPPHLSDEPLENVQEQDLRCRPQDEWTSDVIEEGTKEEEEGVQEKTVSTA 375

  Fly   310 QSVRTLK---------------------------------------------------------- 316
            :|.:|.|                                                          
Zfish   376 KSKKTRKCPKDCLCEYAAQHATCENRGHTKVPSGFPRKTLLLDMRGNHFHYLPSKSFPGIPEVVS 440

  Fly   317 --------------------------LSDNWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDA-L 354
                                      ||||.|.:::....:....:.||.|..:::......| |
Zfish   441 LHLDSCKIHEIEGGAFQGMKNLIYLYLSDNQLSSLDAKVFEGAHEIMYLHLEDNKLTHFPSSATL 505

  Fly   355 GRLELLESLFLDRNLLMR--------------------------VPSSLPPS--LEHLFLQHNQI 391
            ..:..|..|.|:|||:.:                          ||.:|.|:  |:.|.|:.|.:
Zfish   506 THIPKLLELHLERNLIAKLEPSGLLSPVLQLTGLYLNNNSIATIVPKALDPAPKLDVLHLEDNVL 570

  Fly   392 MELPPQAFVGLVNLQTLDLSNNRLIFLPPLSL-----------------------------PKLL 427
            .::|..|......|..|.||.|.:.::.|.:.                             |:||
Zfish   571 TDVPSDALDHAPLLTELHLSGNLIRWIGPRAFRVVAESLKNLLIDRMGLQKMSVRSLAGFGPRLL 635

  Fly   428 TLNLESSGVESVSQSIVHTLPQLRDLLLEDNPIKCS-DLLGIAEWASPCR-SVDA-----GQSNG 485
            :|:||.:.:|.:..  :..|..|::|.|..||:.|. .||....|..... .|:|     .:..|
Zfish   636 SLSLEDNLLEELPD--LSPLAGLQNLSLNKNPLMCDCKLLPFYRWLEKMSLRVEAVCFYPSELRG 698

  Fly   486 ASVSGRVDLKTEYLQ-FHNFYEN---FSSRECGIRKPENDTKPPSCSLTRASATLTTTP-RSMSK 545
            .||......|...:: .|:|.|.   ..:.|..|..|...|:|....|..|...:..|| ::.||
Zfish   699 QSVMESAIYKNCSIENAHSFNETSIPTKAHEPNIPNPTQPTEPSYAKLKLAKTKIAATPKKTKSK 763

  Fly   546 VEKSQEA 552
            ..|.:.|
Zfish   764 EFKPERA 770

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
2mitNP_001262529.1 LRR_RI 124..355 CDD:238064 81/410 (20%)
leucine-rich repeat 124..143 CDD:275380 6/21 (29%)
leucine-rich repeat 144..167 CDD:275380 10/27 (37%)
leucine-rich repeat 172..194 CDD:275380 8/21 (38%)
LRR_8 193..253 CDD:290566 23/82 (28%)
leucine-rich repeat 195..218 CDD:275380 9/22 (41%)
leucine-rich repeat 219..242 CDD:275380 7/22 (32%)
LRR_8 241..301 CDD:290566 21/62 (34%)
leucine-rich repeat 243..311 CDD:275380 25/114 (22%)
leucine-rich repeat 312..335 CDD:275380 7/106 (7%)
LRR_8 334..415 CDD:290566 26/109 (24%)
leucine-rich repeat 336..359 CDD:275380 5/23 (22%)
leucine-rich repeat 360..380 CDD:275380 9/45 (20%)
LRR_8 379..460 CDD:290566 25/111 (23%)
LRR_4 379..>415 CDD:289563 12/37 (32%)
leucine-rich repeat 381..404 CDD:275380 6/22 (27%)
leucine-rich repeat 405..449 CDD:275380 14/72 (19%)
chadlaXP_017210255.1 LRRNT 22..49 CDD:279764
leucine-rich repeat 55..76 CDD:275380 5/16 (31%)
LRR_8 75..135 CDD:290566 16/60 (27%)
leucine-rich repeat 77..100 CDD:275380 5/23 (22%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
leucine-rich repeat 125..148 CDD:275380 9/22 (41%)
leucine-rich repeat 149..172 CDD:275380 2/22 (9%)
LRR_8 172..231 CDD:290566 18/59 (31%)
leucine-rich repeat 173..196 CDD:275380 8/23 (35%)
leucine-rich repeat 197..220 CDD:275380 9/22 (41%)
leucine-rich repeat 221..243 CDD:275380 0/21 (0%)
LRR_8 242..300 CDD:290566 22/59 (37%)
leucine-rich repeat 244..267 CDD:275380 7/22 (32%)
leucine-rich repeat 417..437 CDD:275380 0/19 (0%)
LRR_8 436..496 CDD:290566 8/59 (14%)
leucine-rich repeat 438..461 CDD:275380 0/22 (0%)
LRR_RI <451..658 CDD:238064 41/208 (20%)
leucine-rich repeat 462..485 CDD:275380 5/22 (23%)
leucine-rich repeat 486..510 CDD:275380 5/23 (22%)
leucine-rich repeat 511..535 CDD:275380 6/23 (26%)
LRR_8 535..594 CDD:290566 15/58 (26%)
leucine-rich repeat 536..559 CDD:275380 4/22 (18%)
leucine-rich repeat 560..583 CDD:275380 6/22 (27%)
leucine-rich repeat 584..608 CDD:275380 6/23 (26%)
leucine-rich repeat 609..633 CDD:275380 0/23 (0%)
leucine-rich repeat 634..656 CDD:275380 7/23 (30%)
LRRCT 664..>699 CDD:214507 8/34 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170596587
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

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