DRSC/TRiP Functional Genomics Resources

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Protein Alignment 2mit and CG5810

DIOPT Version :9

Sequence 1:NP_001262529.1 Gene:2mit / 41616 FlyBaseID:FBgn0260793 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_650952.2 Gene:CG5810 / 42513 FlyBaseID:FBgn0038866 Length:428 Species:Drosophila melanogaster


Alignment Length:392 Identity:90/392 - (22%)
Similarity:159/392 - (40%) Gaps:120/392 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 DFQVITAMDLSSNQLESLSLDNFNQLRQLDLGNNSLEVIPLSLADTN---MSLPFVTLDLSCNKF 180
            :|.|   ::....|:||:..|....|::|:.|.|:|.|:     |:|   ::.....|:||.|:.
  Fly    91 EFHV---LECELQQIESVCFDGAKNLKRLNFGGNALRVL-----DSNTFELATQLEELNLSDNQL 147

  Fly   181 SQISTSFFAQRLPQLKNLNLAHNELLNISRESFYNLLELQTLVLSHNNISDIDYETFL-ALPNLQ 244
            ..:.|:.| :.|..|:.:||::|.|:.:|:..|..|..|:::.:..|.:.::..|.|. ...:|.
  Fly   148 EDLPTTIF-RPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGELFRDQRKHLS 211

  Fly   245 YLDLSHNRLSGSAIRALQGIP-----DLVSLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQV 304
            ......|:|    :|    ||     ::..||:::||                            
  Fly   212 EFSAQSNQL----VR----IPFNIFREIDHLSLSFNP---------------------------- 240

  Fly   305 PAALAQSVRTLKLSD--NWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLELLESLFLDR 367
                  .:|.|.||.  |.|:|.|| |::|..|       ..|:..|:.:|..:|..|:      
  Fly   241 ------QLRRLHLSAKINELEATNC-DLESVEL-------DGRVIGVQLEANPKLHELK------ 285

  Fly   368 NLLMRVPSSLPPSLEHLFLQHNQIMELPPQAFVG----LVNLQTLDLSNNRLIFLPPLSLPKLLT 428
                   .|.|..||||:|.:..:..|.   |:.    ||:|...|:.|  |..||.::..|   
  Fly   286 -------ISQPQDLEHLYLANTNLYRLD---FLSKASKLVDLDVTDIVN--LADLPKITSAK--- 335

  Fly   429 LNLE--SSGVESVSQSIVHTLPQLRDL----------------------LLEDNPIKCSDLLGIA 469
             .||  |...::::.:.:..||.|:||                      .:|:..:.|..|..:.
  Fly   336 -GLERLSFTYDNLTSNHMDMLPHLKDLNYLEISHEKGKEIFIKDLDEDFFVEEAELNCGQLADLL 399

  Fly   470 EW 471
            |:
  Fly   400 EF 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
2mitNP_001262529.1 LRR_RI 124..355 CDD:238064 56/241 (23%)
leucine-rich repeat 124..143 CDD:275380 4/18 (22%)
leucine-rich repeat 144..167 CDD:275380 8/25 (32%)
leucine-rich repeat 172..194 CDD:275380 7/21 (33%)
LRR_8 193..253 CDD:290566 14/60 (23%)
leucine-rich repeat 195..218 CDD:275380 8/22 (36%)
leucine-rich repeat 219..242 CDD:275380 4/23 (17%)
LRR_8 241..301 CDD:290566 10/64 (16%)
leucine-rich repeat 243..311 CDD:275380 10/72 (14%)
leucine-rich repeat 312..335 CDD:275380 11/24 (46%)
LRR_8 334..415 CDD:290566 20/84 (24%)
leucine-rich repeat 336..359 CDD:275380 4/22 (18%)
leucine-rich repeat 360..380 CDD:275380 3/19 (16%)
LRR_8 379..460 CDD:290566 25/108 (23%)
LRR_4 379..>415 CDD:289563 12/39 (31%)
leucine-rich repeat 381..404 CDD:275380 8/26 (31%)
leucine-rich repeat 405..449 CDD:275380 11/45 (24%)
CG5810NP_650952.2 leucine-rich repeat 65..88 CDD:275380
LRR_8 87..147 CDD:290566 18/63 (29%)
leucine-rich repeat 89..112 CDD:275380 6/23 (26%)
leucine-rich repeat 113..136 CDD:275380 8/27 (30%)
LRR_8 135..195 CDD:290566 17/60 (28%)
LRR_4 135..175 CDD:289563 12/40 (30%)
leucine-rich repeat 137..160 CDD:275380 7/23 (30%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
leucine-rich repeat 185..209 CDD:275380 4/23 (17%)
leucine-rich repeat 210..231 CDD:275380 6/28 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453504
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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