Protein Alignment 2mit and CG32055

DIOPT Version :10

• Sequence 1: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_729599.1
• Gene: CG32055 / 39188
• FlyBaseID: FBgn0052055
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 143/569 - (25%)
• Similarity: 213/569 - (37%)
• Gaps: 191/569 - (33%)

  Fly     2 VKIVNQHCDL---------GLALLLA------------------WTWLTRLVVAAHLVDIPTSSR 39
            ||:||:|..:         ||:.||.                  :..|.:|.:        |.::
  Fly    53 VKVVNEHTGIERAEDGELPGLSTLLQLDLSESGGVTLGEKGLQDFKALQKLNL--------THAQ 109

  Fly    40 LAAEREEQ----------QLSRQDV-----------GRLSYQSIHRMLRDENEPDSFR--GELRY 81
            |...:.||          .:|..|:           |.|.|.:....|....||::||  ..||:
  Fly   110 LDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNLRF 174

  Fly    82 QQ--KRHKRELELNAPANK--LNLTHRDLRTFNSTGGQWKGDFQVITAMD---LSSNQLESLSLD 139
            ..  ..::..:.|...||.  |::::.:||.|     || ...:|:..::   |.||.||.|.:.
  Fly   175 LDLTTNYQENITLGENANLRFLSISNNNLRDF-----QW-CHLRVLPKLEELHLHSNWLEHLDMG 233

  Fly   140 NF---NQLRQLDLGNNSL------------EVIPLSLADTNMSLPFVTLDLSCNKFSQISTSFFA 189
            .|   ..||.|::.||:|            |:.||.|           ||.|.|....:..|.|.
  Fly   234 IFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLEL-----------LDYSSNIVKVLDDSVFC 287

  Fly   190 QRLPQLKNLNLAHNELLNISRESFYNLLELQTLVLSHNNISDIDYETFLALPNLQYLDLSHNRLS 254
             ||.:|:.|||..|::..|...:|..|..||||.|..|.||.:..:.|..|..|:.||||.|.:.
  Fly   288 -RLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILPDDVFANLTALEKLDLSKNNIQ 351

  Fly   255 GSAIRALQGIPDLVSLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQVPAALAQSVRTLKLSD 319
            ...:|..                                                 ..|.|:
  Fly   352 KLGLRVF-------------------------------------------------GERILR--- 364

  Fly   320 NWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLELLESLFLDRNLL----MRVPSSLPPS 380
                           .|.|||||::.||.:...||..:..::.|.|.||.|    :|:.:.| ..
  Fly   365 ---------------KLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDLRMFAPL-RQ 413

  Fly   381 LEHLFLQHNQIMELPPQAFVGLVNLQTLDLSNNRLIFLPPLSLPKLLTLNLESSGVESVSQSIVH 445
            |:.|.:..|::.|:..:....|..|..|:|:||||.|||          :|:||          .
  Fly   414 LQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLP----------DLKSS----------Q 458

  Fly   446 TLPQLRDLLLEDNPIKCSDLLGIAEWASPCRSVDAGQSNGASVSGRVDL 494
            .|.|||::.||.||.:|..|..|..|.:. |.|...:.:.|..|||..|
  Fly   459 NLLQLRNITLEGNPWQCLCLDEITSWLNG-RHVSYARPSSAYFSGRKPL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
2mit	NP_001262529.1	LRR	<106..458	CDD:443914	99/373 (27%)
		leucine-rich repeat	124..143	CDD:275380	7/24 (29%)
		leucine-rich repeat	144..167	CDD:275380	10/34 (29%)
		leucine-rich repeat	172..194	CDD:275380	8/21 (38%)
		leucine-rich repeat	195..218	CDD:275380	8/22 (36%)
		leucine-rich repeat	219..242	CDD:275380	10/22 (45%)
		leucine-rich repeat	243..311	CDD:275380	7/67 (10%)
		leucine-rich repeat	312..335	CDD:275380	2/22 (9%)
		leucine-rich repeat	336..359	CDD:275380	10/22 (45%)
		leucine-rich repeat	360..380	CDD:275380	7/23 (30%)
		leucine-rich repeat	381..404	CDD:275380	5/22 (23%)
		leucine-rich repeat	405..449	CDD:275380	14/43 (33%)
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	2/22 (9%)
		leucine-rich repeat	100..123	CDD:275380	6/30 (20%)
		LRR_8	126..180	CDD:404697	12/53 (23%)
		leucine-rich repeat	128..147	CDD:275380	2/18 (11%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR	171..>486	CDD:443914	111/420 (26%)
		leucine-rich repeat	172..192	CDD:275380	3/19 (16%)
		leucine-rich repeat	193..216	CDD:275380	7/28 (25%)
		leucine-rich repeat	217..240	CDD:275380	7/22 (32%)
		leucine-rich repeat	241..267	CDD:275380	7/25 (28%)
		leucine-rich repeat	268..291	CDD:275380	10/34 (29%)
		leucine-rich repeat	292..315	CDD:275380	8/22 (36%)
		leucine-rich repeat	316..339	CDD:275380	10/22 (45%)
		leucine-rich repeat	340..365	CDD:275380	9/91 (10%)
		leucine-rich repeat	366..389	CDD:275380	10/22 (45%)
		leucine-rich repeat	390..413	CDD:275380	7/23 (30%)
		leucine-rich repeat	414..437	CDD:275380	5/22 (23%)