Protein Alignment 2mit and wu:fc23c09

DIOPT Version :10

• Sequence 1: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001410060.1
• Gene: wu:fc23c09 / 101882092
• ZFINID: ZDB-GENE-030131-2988
• Length: 678
• Species: Danio rerio
• Alignment Length: 416
• Identity: 107/416 - (25%)
• Similarity: 177/416 - (42%)
• Gaps: 90/416 - (21%)

  Fly    30 HLVDIPTSSRLAAEREEQQLSRQDVGRLSYQSIHRMLRDENEPDSFRGELRYQQKRHKRELELNA 94
            |||.||..                   :.|.|.:.:|.: |:.||.
Zfish   324 HLVKIPYG-------------------IPYNSRYILLMN-NKIDSI------------------- 349

  Fly    95 PANKLNLTHRDLRTFNSTGGQWKGDFQVITAMDLSSNQLESLSLDNFNQLRQLDLGNNSLEVIPL 159
               :|||    |..::|.      :|.|:....|:.:.::. :.:...:|::|.:..|.|..||
Zfish   350 ---QLNL----LSQYDSM------EFLVLRNNRLTDSAVKK-AFEGIQRLKRLYVERNLLRSIP- 399

  Fly   160 SLADTNMSLPFVTLDLSCNKFSQISTSFFAQRLPQLKNLNLAHNELLNISRESFYNLLELQTLVL 224
                |::......|.|..|:.|.:|.:.| :|.|.|:.|:|::|.||.|.......|..|:||.|
Zfish   400 ----TDLPATLEELRLDWNQISAMSNAAF-ERCPSLQILSLSNNTLLTIPPGVLLPLGSLRTLTL 459

  Fly   225 SHNNISDIDYETFLALPNLQYLDLSHNRLSGSAIRALQGIP-------DLVSLSIAYNPDVGVAM 282
            |:|.::.:..:..|:|..|.        |.|:.|:.|||..       .::.||:....|.|:..
Zfish   460 SYNQLASVPMQLPLSLRELY--------LRGNRIQRLQGDMFWGESELQILDLSLNRLTDKGLGK 516

  Fly   283 QEFVASWSLKELDASGTGLCQVPAALAQSVRTLKLSDNWLKAINCGDMDSYPLLQYLDLSHSRIA 347
            ...:.:..|:.|:..|..|.:||..|..:::||.|..|::.:|......|.|.|::|.|:.::||
Zfish   517 AALLNATGLESLNLEGNLLKRVPRHLPHTIKTLNLEGNFILSITKDAFVSMPQLEHLGLARNKIA 581

  Fly   348 QVEDDALGRLELLESLFLDRNLLMRVPSSLPPSLEHLFLQHNQIMELPPQAFV-GLVNLQTLDLS 411
            :|...|...|.||..|.:..|.|.:||..||..|......||.|..:|..||. |..|:.
Zfish   582 KVALGAFRVLPLLHQLDMSYNALEQVPRQLPLWLHSATFMHNNIRSIPRDAFCWGRDNVS----- 641

  Fly   412 NNRLIFLPPLSLPKLLTLNLESSGVE 437
                    |||  :|:.:.||.:.::
Zfish   642 --------PLS--RLVKVQLEYNMID 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
2mit	NP_001262529.1	LRR	<106..458	CDD:443914	93/340 (27%)
		leucine-rich repeat	124..143	CDD:275380	1/18 (6%)
		leucine-rich repeat	144..167	CDD:275380	7/22 (32%)
		leucine-rich repeat	172..194	CDD:275380	7/21 (33%)
		leucine-rich repeat	195..218	CDD:275380	8/22 (36%)
		leucine-rich repeat	219..242	CDD:275380	8/22 (36%)
		leucine-rich repeat	243..311	CDD:275380	18/74 (24%)
		leucine-rich repeat	312..335	CDD:275380	6/22 (27%)
		leucine-rich repeat	336..359	CDD:275380	8/22 (36%)
		leucine-rich repeat	360..380	CDD:275380	8/19 (42%)
		leucine-rich repeat	381..404	CDD:275380	8/23 (35%)
		leucine-rich repeat	405..449	CDD:275380	6/33 (18%)
wu:fc23c09	NP_001410060.1	LRRNT	307..335	CDD:214470	5/29 (17%)
		leucine-rich repeat	316..334	CDD:275380	5/28 (18%)
		leucine-rich repeat	337..359	CDD:275380	8/48 (17%)
		LRR	339..>560	CDD:443914	65/268 (24%)
		leucine-rich repeat	360..384	CDD:275380	3/30 (10%)
		leucine-rich repeat	385..404	CDD:275380	7/23 (30%)
		leucine-rich repeat	406..429	CDD:275380	7/23 (30%)
		leucine-rich repeat	430..453	CDD:275380	8/22 (36%)
		leucine-rich repeat	454..474	CDD:275380	6/19 (32%)
		leucine-rich repeat	475..498	CDD:275380	8/30 (27%)
		leucine-rich repeat	499..524	CDD:275380	4/24 (17%)
		leucine-rich repeat	525..544	CDD:275380	7/18 (39%)
		leucine-rich repeat	546..569	CDD:275380	6/22 (27%)
		LRR_8	547..604	CDD:404697	19/56 (34%)
		leucine-rich repeat	570..593	CDD:275380	8/22 (36%)
		leucine-rich repeat	618..645	CDD:275380	11/41 (27%)
		leucine-rich repeat	646..671	CDD:275380	3/12 (25%)