Protein Alignment 2mit and igfals

DIOPT Version :9

• Sequence 1: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_002940278.2
• Gene: igfals / 100489984
• XenbaseID: XB-GENE-1008441
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 461
• Identity: 122/461 - (26%)
• Similarity: 191/461 - (41%)
• Gaps: 107/461 - (23%)

  Fly   145 RQLDLGNNSLEVIPLSLADTNMS-LPFVTLDLSCNKFSQISTSFFAQRLPQLK---NLNLAHNEL 205
            |.|.|..|:|..:... |..|:| |.|:.|     :.||:: |...|.|..||   :|:|..|.:
 Frog    70 RSLWLDGNNLTTVQAG-AFRNLSHLDFLNL-----QSSQVA-SLEQQALHGLKALAHLHLERNMI 127

  Fly   206 LNISRESFYNLLELQTLVLSHNNISDIDYETFLALPNLQYLDLSHNRLSGSAIRALQGIPDLV-- 268
            .:::..:|.:...|.:|.|::|.::.|:...|..|.||.||:|..|        .|..:||:|
 Frog   128 KSLAPSTFTHTQNLVSLTLNNNFLTKIEDGLFSGLSNLWYLNLGWN--------LLVVLPDMVFH 184

  Fly   269 ------SLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQVPAAL---AQSVRTLKLSDNWLKA 324
                  .|.:|.|..|.:....|::...|||||.||..|..:.|.:   .|....|.|:.|.:..
 Frog   185 DLLNLRELVLAGNRLVYLQPSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHIST 249

  Fly   325 INCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLELLESLFLDRNLLMRVPSSLPP---------- 379
            :..........|::|||||:|:..:.:|....|..|..|.|..|.|    :||.|
 Frog   250 VAPRAFSGMKNLRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSL----TSLRPRIFKDLQFLV 310

  Fly   380 ---------------------SLEHLFLQHNQIMELPPQAFVGLVNLQTLDLSNNRLIFLPP--- 420
                                 .||.|.|.||.:.|:.|.:|:||:|:..::||.|.|..|..
 Frog   311 ELNLGQNKIKILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCF 375

  Fly   421 LSLPKLLTLNLESSGVESVSQSIVHTLPQLRDLLLEDNPI------KCSDLLGIAEWASPCRSVD 479
            ..|.||.:|::|||.:..:...:...|..:|.|.|::|.|      ..:||.|:.|
 Frog   376 KGLGKLHSLHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIEDHSFTDLHGLLE--------- 431

  Fly   480 AGQSNGASVSGRVDLKTEYLQFHNFYENFSSRECGIRKPENDTKPPSCSLTRASATLTTTPRSMS 544
                        :||::..|. |....:|:.           .|..|..|..::..||.:|...|
 Frog   432 ------------LDLRSNKLT-HLTTRSFTG-----------LKNLSYLLLSSNQILTISPEVFS 472

  Fly   545 KVEKSQ 550
            .|::.|
 Frog   473 PVQQLQ 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
2mit	NP_001262529.1	LRR_RI	124..355	CDD:238064	65/224 (29%)
		leucine-rich repeat	124..143	CDD:275380
		leucine-rich repeat	144..167	CDD:275380	7/21 (33%)
		leucine-rich repeat	172..194	CDD:275380	6/21 (29%)
		LRR_8	193..253	CDD:290566	19/62 (31%)
		leucine-rich repeat	195..218	CDD:275380	6/25 (24%)
		leucine-rich repeat	219..242	CDD:275380	7/22 (32%)
		LRR_8	241..301	CDD:290566	22/67 (33%)
		leucine-rich repeat	243..311	CDD:275380	23/78 (29%)
		leucine-rich repeat	312..335	CDD:275380	3/22 (14%)
		LRR_8	334..415	CDD:290566	32/111 (29%)
		leucine-rich repeat	336..359	CDD:275380	9/22 (41%)
		leucine-rich repeat	360..380	CDD:275380	8/50 (16%)
		LRR_8	379..460	CDD:290566	30/114 (26%)
		LRR_4	379..>415	CDD:289563	16/66 (24%)
		leucine-rich repeat	381..404	CDD:275380	11/22 (50%)
		leucine-rich repeat	405..449	CDD:275380	13/46 (28%)
igfals	XP_002940278.2	leucine-rich repeat	69..92	CDD:275380	7/22 (32%)
		PLN00113	71..>534	CDD:215061	121/460 (26%)
		leucine-rich repeat	93..116	CDD:275380	9/28 (32%)
		leucine-rich repeat	117..140	CDD:275380	4/22 (18%)
		leucine-rich repeat	141..164	CDD:275380	7/22 (32%)
		leucine-rich repeat	165..188	CDD:275380	9/30 (30%)
		leucine-rich repeat	189..212	CDD:275380	5/22 (23%)
		leucine-rich repeat	213..236	CDD:275380	9/22 (41%)
		leucine-rich repeat	237..260	CDD:275380	3/22 (14%)
		leucine-rich repeat	261..284	CDD:275380	9/22 (41%)
		leucine-rich repeat	285..308	CDD:275380	8/26 (31%)
		leucine-rich repeat	309..332	CDD:275380	0/22 (0%)
		leucine-rich repeat	333..354	CDD:275380	9/20 (45%)
		leucine-rich repeat	357..380	CDD:275380	6/22 (27%)
		leucine-rich repeat	381..404	CDD:275380	6/22 (27%)
		leucine-rich repeat	405..428	CDD:275380	7/22 (32%)
		leucine-rich repeat	429..450	CDD:275380	6/53 (11%)
		leucine-rich repeat	453..472	CDD:275380	5/18 (28%)
		leucine-rich repeat	477..500	CDD:275380	1/2 (50%)
		leucine-rich repeat	525..537	CDD:275378

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910