DRSC/TRiP Functional Genomics Resources

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Protein Alignment 2mit and lrrc32.1

DIOPT Version :9

Sequence 1:NP_001262529.1 Gene:2mit / 41616 FlyBaseID:FBgn0260793 Length:1155 Species:Drosophila melanogaster
Sequence 2:XP_004912272.1 Gene:lrrc32.1 / 100489763 XenbaseID:XB-GENE-994459 Length:666 Species:Xenopus tropicalis


Alignment Length:623 Identity:149/623 - (23%)
Similarity:236/623 - (37%) Gaps:200/623 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 HKRELE---LNAP--ANKLNLTHRDLRTFNSTGGQWKGDFQVITAMDLSSNQLESLSLDNF---N 142
            |.:.|:   |:.|  ...|:|:|.||.  |.|..... .:..:.::|||||||..:...:|   :
 Frog    37 HNKSLQQVPLDLPPGIQTLDLSHNDLE--NITEDHLM-KYSFLESLDLSSNQLSFIQPHSFRKMH 98

  Fly   143 QLRQLDLGNNSLEVIPLSLADTNMS----LPFV-TLDLSCNKFSQISTSFFAQRLPQLKNLNLAH 202
            :|::::|..|.|:    |.....:|    ||:| |||||.|........:|.|..|:|:.|:|..
 Frog    99 KLKEINLSGNDLD----SFVHHRVSGIGVLPYVQTLDLSRNSLYNDMIGYFLQEAPRLQYLSLHE 159

  Fly   203 NELLNISRESF---------------------------------------------YNLLELQTL 222
            |.:..||.:.|                                             :||.:|:.|
 Frog   160 NSITTISSDLFQGSPLLAEVDLHNNIIMDIEEGSFEYLKHLSMIDLSMNSITCISDFNLRQLKVL 224

  Fly   223 VLSHNNI-------SDIDYETFLALPNLQYLDLSHNRLSGSAIRALQGIPDLVSLSIAYN----- 275
            .||.|:|       |:.:|       .|:.:|||||:|  |:...|..:.:::.:.::.|     
 Frog   225 NLSKNSIKTFHTPDSEDEY-------LLEKVDLSHNKL--SSFPQLPRVNNVIFIDLSKNYIHLG 280

  Fly   276 -------PD-VGVAMQ-EF----------VASWSLKELDASGTGLCQVP---------------- 305
                   || :..:.| ||          |....|..||.|...:..:|                
 Frog   281 TETPGEDPDWMNYSFQLEFEEQNPKNISTVPLPKLNHLDLSYNSIKSIPDDFFLTMPSLTFLNLS 345

  Fly   306 ------------AALAQSVRTLKLSDNWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLE 358
                        :.|: |:.||.||.|.::.::.| .:|.|.||.|.|.|:::..:|.....|||
 Frog   346 KNCIQVLSLGHFSGLS-SLATLDLSANSIQNLSLG-ANSLPSLQRLYLQHNQLRLLEPRIFQRLE 408

  Fly   359 LLESLFLDRNLLMRVPSSLP-------------------PSLEHLFLQHNQIMELPPQAFVGLVN 404
            .:..|.|..|.:....:.|.                   |:|:||.|:.|.|..:|..||.| .:
 Frog   409 SIVLLHLQGNHVGPCMAGLGKAKRRTHAEEYRCVEFFNIPTLQHLNLRENMIQRIPASAFWG-TS 472

  Fly   405 LQTLDLSNNRLIFLPP---LSLPKLL-TLNLESSGVESVSQSIVHTLP---QLRDLLLEDNPIKC 462
            |:.||||.|..|.:.|   ..|.|.| .|.:|.:|:.|::..    ||   .|:.|.|..|    
 Frog   473 LKVLDLSMNLGIKVKPNALFGLEKTLEVLFMEGNGLPSLNVD----LPLFTHLKYLNLSGN---- 529

  Fly   463 SDLLGIAEWASPCR----SVDAGQSNGASVSGRVDLKTEYLQFHNFYENFSSRECGIRKPENDTK 523
             .|..:.||.|.||    .:......|..|| .:.:....|:..:.|.|                
 Frog   530 -QLSELPEWNSDCRLETLDLSLNSFTGLEVS-NIPVLENTLKTLSLYGN---------------- 576

  Fly   524 PPSC--------SLTRASATLTTTPRSMSKVEKSQEAQ 553
            |.||        .:.|.:.|:.....:...:.|..|.:
 Frog   577 PLSCCANTWISHMIRRTAVTIVALNATTCNISKLYEGE 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
2mitNP_001262529.1 LRR_RI 124..355 CDD:238064 80/342 (23%)
leucine-rich repeat 124..143 CDD:275380 8/21 (38%)
leucine-rich repeat 144..167 CDD:275380 5/22 (23%)
leucine-rich repeat 172..194 CDD:275380 8/21 (38%)
LRR_8 193..253 CDD:290566 24/111 (22%)
leucine-rich repeat 195..218 CDD:275380 9/67 (13%)
leucine-rich repeat 219..242 CDD:275380 8/29 (28%)
LRR_8 241..301 CDD:290566 20/83 (24%)
leucine-rich repeat 243..311 CDD:275380 22/119 (18%)
leucine-rich repeat 312..335 CDD:275380 7/22 (32%)
LRR_8 334..415 CDD:290566 31/99 (31%)
leucine-rich repeat 336..359 CDD:275380 8/22 (36%)
leucine-rich repeat 360..380 CDD:275380 4/38 (11%)
LRR_8 379..460 CDD:290566 32/87 (37%)
LRR_4 379..>415 CDD:289563 17/35 (49%)
leucine-rich repeat 381..404 CDD:275380 10/22 (45%)
leucine-rich repeat 405..449 CDD:275380 17/50 (34%)
lrrc32.1XP_004912272.1 LRR_8 50..110 CDD:404697 18/62 (29%)
leucine-rich repeat 52..75 CDD:275380 7/25 (28%)
leucine-rich repeat 76..99 CDD:275380 8/22 (36%)
PLN00113 99..>579 CDD:215061 124/521 (24%)
leucine-rich repeat 100..151 CDD:275380 17/54 (31%)
leucine-rich repeat 152..175 CDD:275380 7/22 (32%)
leucine-rich repeat 176..199 CDD:275380 0/22 (0%)
leucine-rich repeat 200..220 CDD:275380 2/19 (11%)
leucine-rich repeat 245..314 CDD:275380 16/70 (23%)
leucine-rich repeat 315..338 CDD:275380 5/22 (23%)
leucine-rich repeat 339..362 CDD:275380 1/23 (4%)
leucine-rich repeat 363..385 CDD:275380 7/22 (32%)
leucine-rich repeat 386..409 CDD:275380 8/22 (36%)
leucine-rich repeat 410..449 CDD:275380 4/38 (11%)
leucine-rich repeat 450..472 CDD:275380 10/22 (45%)
leucine-rich repeat 473..520 CDD:275380 17/50 (34%)
leucine-rich repeat 498..512 CDD:275378 5/13 (38%)
leucine-rich repeat 521..542 CDD:275380 8/25 (32%)
leucine-rich repeat 543..566 CDD:275380 3/23 (13%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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