Protein Alignment 2mit and si:dkey-182i3.11

DIOPT Version :9

• Sequence 1: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_021322095.1
• Gene: si:dkey-182i3.11 / 100334238
• ZFINID: ZDB-GENE-121214-258
• Length: 710
• Species: Danio rerio
• Alignment Length: 446
• Identity: 120/446 - (26%)
• Similarity: 202/446 - (45%)
• Gaps: 69/446 - (15%)

  Fly    90 LELNAPAN-----KLNLTHRDLRTFNSTGGQWKG-----------------------DFQVITAM 126
            :|:|...|     ||.|:...|::..:  |.:||                       :...:|::
Zfish   214 IEMNVFENCTYLAKLYLSKNKLKSVGN--GSFKGATGLNHLDLGLNGLAGIPTIVLQETSNLTSL 276

  Fly   127 DLSSNQLESLSLDNFNQ---LRQLDLGNNSLEVIPLSLADTNMSLPFVTLDLSCNKFSQISTSFF 188
            .|..|.:.|:..:.|::   |:.|||..|.|  :.:|..........|.||||.|:...::...|
Zfish   277 YLQKNDITSIPDNVFSEILSLKHLDLSYNGL--VSISNGSFRSLSQLVYLDLSFNQLQTLTQHVF 339

  Fly   189 AQRLPQLKNLNLAHNELLNISRESFYNLLELQTLVLSHNNISDIDYETFLALPNLQYLDLSHNRL 253
             :.|.:|:||||.||:|.::....|.||..|:.|.|..||||.|..:.|..|..|:.|.|.:|.:
Zfish   340 -EDLGKLENLNLYHNKLTSLPNNMFKNLTMLKELQLDSNNISVIPPDLFHPLSALKDLQLDNNHI 403

  Fly   254 SGSAIRALQGIPDLVSLSIAYNPDVGVA-------MQE---------FVASWS------LKELDA 296
            |.......:.:..|..|.|:.|....:.       ::|         |::.:|      |:.|..
Zfish   404 SKLHSHTFKKLRQLKQLDISSNDLTKIPNHLFHKNLKELNLENNHISFISKFSFKNLHRLQSLKL 468

  Fly   297 SGTGLCQVPAALAQS---VRTLKLSDNWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLE 358
            |...|.::...|..:   :|.|.|::|.::.|..|.......|:.||||::::..:..||...|.
Zfish   469 SHNNLSKLYRELLTNLTRLRELLLNENQIETIPVGFFKGLENLRVLDLSNNKMHFILPDAFNDLS 533

  Fly   359 LLESLFLDRNLLMRVPSSLPPSLEH---LFLQHNQIMELPPQAFVGLVNLQTLDLSNNRLIFLPP 420
            .|:.|.|..|.|..:|..:..||.:   |.||:|::..||.:.|..||.|:.|.|..|.:..:.|
Zfish   534 ALKDLDLSFNFLHNLPEDIFASLRNLTKLHLQNNKLRYLPSRLFSALVGLEELHLDRNYIQRIHP 598

  Fly   421 L---SLPKLLTLNLESSGVESVSQSIVHTLPQLRDLLLEDNPIKCSD--LLGIAEW 471
            .   .|.||..|:::|:.:.|:....:..|.:|:.:.|:.||..||.  :|.|::|
Zfish   599 TQFEGLVKLHELDMKSNQLRSMEDGTLMPLRKLKRIHLDGNPWDCSTVVILYISQW 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
2mit	NP_001262529.1	LRR_RI	124..355	CDD:238064	71/258 (28%)
		leucine-rich repeat	124..143	CDD:275380	5/18 (28%)
		leucine-rich repeat	144..167	CDD:275380	7/22 (32%)
		leucine-rich repeat	172..194	CDD:275380	7/21 (33%)
		LRR_8	193..253	CDD:290566	25/59 (42%)
		leucine-rich repeat	195..218	CDD:275380	11/22 (50%)
		leucine-rich repeat	219..242	CDD:275380	10/22 (45%)
		LRR_8	241..301	CDD:290566	15/81 (19%)
		leucine-rich repeat	243..311	CDD:275380	17/89 (19%)
		leucine-rich repeat	312..335	CDD:275380	6/22 (27%)
		LRR_8	334..415	CDD:290566	29/83 (35%)
		leucine-rich repeat	336..359	CDD:275380	8/22 (36%)
		leucine-rich repeat	360..380	CDD:275380	6/19 (32%)
		LRR_8	379..460	CDD:290566	26/86 (30%)
		LRR_4	379..>415	CDD:289563	15/38 (39%)
		leucine-rich repeat	381..404	CDD:275380	9/25 (36%)
		leucine-rich repeat	405..449	CDD:275380	12/46 (26%)
si:dkey-182i3.11	XP_021322095.1	PLN00113	97..>617	CDD:331614	109/407 (27%)
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..176	CDD:275380
		leucine-rich repeat	177..200	CDD:275380
		leucine-rich repeat	201..224	CDD:275380	3/9 (33%)
		leucine-rich repeat	225..248	CDD:275380	7/24 (29%)
		leucine-rich repeat	249..272	CDD:275380	0/22 (0%)
		leucine-rich repeat	273..296	CDD:275380	5/22 (23%)
		leucine-rich repeat	297..320	CDD:275380	7/24 (29%)
		leucine-rich repeat	321..344	CDD:275380	8/23 (35%)
		leucine-rich repeat	345..368	CDD:275380	11/22 (50%)
		leucine-rich repeat	369..392	CDD:275380	10/22 (45%)
		leucine-rich repeat	393..438	CDD:275380	9/44 (20%)
		leucine-rich repeat	417..436	CDD:275380	4/18 (22%)
		leucine-rich repeat	439..462	CDD:275380	3/22 (14%)
		leucine-rich repeat	463..486	CDD:275380	5/22 (23%)
		leucine-rich repeat	487..510	CDD:275380	6/22 (27%)
		leucine-rich repeat	511..534	CDD:275380	8/22 (36%)
		leucine-rich repeat	535..558	CDD:275380	8/22 (36%)
		leucine-rich repeat	559..582	CDD:275380	8/22 (36%)
		leucine-rich repeat	583..606	CDD:275380	6/22 (27%)
		leucine-rich repeat	607..628	CDD:275380	4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.870