Protein Alignment timeout and ATIM

DIOPT Version :9

• Sequence 1: NP_524341.3
• Gene: timeout / 41615
• FlyBaseID: FBgn0038118
• Length: 1384
• Species: Drosophila melanogaster
• Sequence 2: NP_001330129.1
• Gene: ATIM / 835368
• AraportID: AT5G52910
• Length: 1163
• Species: Arabidopsis thaliana
• Alignment Length: 1433
• Identity: 282/1433 - (19%)
• Similarity: 526/1433 - (36%)
• Gaps: 405/1433 - (28%)

  Fly     1 MSILLADI-----DATCAALGYSDGQKYQAEPDAAEGLKHLIWILRR-DLDNHEYRRHLGRSKVL 59
            :|::.:|:     |.....:|||..:.      ..:.||.|:..||| |.::.|..:.:....::
plant    18 LSVICSDLGLPEEDEDRRRIGYSKSEY------CLDNLKDLLRFLRRDDPESREVFKQVCAWNIV 76

  Fly    60 QTDLVYMLPDYVHHEELSDLLIRLLVILTNPTLLLYREGAPKDNHGRKVFMELIDILQGYKAAFA 124
            ..||:.::..|.....|....:::||.||.|.     |.:..|      ..:.::.|.|.|:|..
plant    77 SKDLIPIIEHYQDEHNLVLNAVKVLVFLTMPI-----EPSSDD------IPQQLEYLWGLKSAIT 130

  Fly   125 KDKVWSALFEKLKQALE-IAFAIRSEEQNLLIERILVLVRNVLQV-PANP-----EAECRADNDA 182
            ...:.:.:...|:..|| :...:.:||...|::.:|.|.||:|.: ..:|     |:.|..   .
plant   131 FSNIVAVIVSLLEAPLENLELDVFNEEDWKLVQLVLTLFRNLLAIHDVSPIQKAGESTCYF---L 192

  Fly   183 SLHDQVIWALHQTGMLDLVLFVISSPDE------EQFHLHGLEIVCLLFREQSAESLADASLQRS 241
            ||.||.:..|.:..::|:|| ||:...|      ...:|..|||...:...|..|.:|.|. ::.
plant   193 SLRDQFLEVLSRENVMDIVL-VITQTIEGFNSLLRHDNLLLLEIYHYILLGQDMELVAKAP-EKL 255

  Fly   242 LSEKQRDQQELLAARRRERARRQ-AR--PPPGRHSRFGGTY----------VIRNMKSVSDRDVI 293
            ...||.....|....:.|..:|: ||  ....|||:||||:          |::.:.|.::..::
plant   256 DQGKQASVDSLKTLMKEEEVKRKLARLNNMNQRHSQFGGTFTRVTMDGTKAVLKGIPSTTESTML 320

  Fly   294 CHQALERVSSIDFDREKQQQKR--SHRHIQEEAQVTRRSAFTVRLCLREYCIEVLRSAYNTLVRQ 356
                            |.||.|  :.:.:.|...::..:...::| |.::..:.:...||.|::.
plant   321 ----------------KPQQGRGATEKIVWEHGPMSVTNDKVLKL-LHDFINQFMSGGYNVLMQS 368

  Fly   357 VRRVLERNAGSSSHDDSYLLWAIRFF--------MEFNRLS----GLQLQLVSE----------- 398
            :...:|:...|..:.|     .:.||        .:|::.|    .::.:..||
plant   369 LCEDIEKEHPSIQNSD-----IVTFFQVAQSITSFQFHKSSASSPAIETEETSELTTNQKAGVNF 428

  Fly   399 -----------SLSVQCFHWVLTRMQHDMDMIVSDKKQARLWAKRLHVALLTFRELLQSL-LALQ 451
                       :::.:.|..|:::.:...|.:...|.     .|.|..|....:.:|..| |.::
plant   429 SKSDICAPIAATINDRMFLLVISKWRCAFDGLKETKD-----FKFLSAASSLVKTMLCLLDLVIK 488

  Fly   452 KLKDDNNARALFDMLLNNVCYVLEYRET-------VLHLLMNYNEAHSTKVFLRDVVETANVFIK 509
            .|.:|:.......:||    |.|.|.:|       :|:|:.:::.....|..|.|:||:.::.:.
plant   489 LLPEDSKEAFTVRILL----YKLFYDQTDQGMCQFILNLVRSFDTHKQPKSELGDLVESIHIIVG 549

  Fly   510 MMERFCQDSVVVQDKKRGRGASR--KKKQAATKSKPPAAPQPTEEELSSKWAELATEVCSLLSTE 572
            :||..           :|||..|  ||.:.|.|.||....:.|..:||......:.|
plant   550 LMENL-----------QGRGTLRVSKKSRKARKKKPKGNKEATVHKLSENHPSTSNE-------- 595

  Fly   573 LEMPEDEQPLPFDAASEKSIDDQREDCMIRINKLLRSEKLDQAIALLRAAREVWPENEVFGAISA 637
                         |::.|||                 ..:|..::......:| |.|:
plant   596 -------------ASTAKSI-----------------PMVDSTVSTEDGPMDV-PPNK------- 622

  Fly   638 APEDELLLLREIFMSNITTVESEDKENEKDQKQDEYED----EDDDLDNEEYEEQDNGLTEKTFK 698
             ||          .||:.|...|.::....:..:..:|    .||..|.||....|    |..||
plant   623 -PE----------ASNLETETDETQQMHSPKSNNVVDDLSSGSDDSSDGEEQTATD----EVDFK 672

  Fly   699 FDDFARRLLNPKIVRACTLVLSDWADIPTRSLKAAVTILHRIAYGCKCAGMLFQAKLFRIFQQVF 763
            ...|.....:..|::....:|..:...|.::....::||.||....:.|.||:|..|...|.::.
plant   673 VSTFISAFASNSIIQNLCWLLKFYKSNPKQTNHHVISILRRITEDLELAPMLYQLSLLITFHKIL 737

  Fly   764 SVERDVHQEELRRLAIF---VVRKFVEVAPTNPKIYAELLFYKGIREANELESGYCDAYEAG--- 822
            ..::....::...:..|   :||..::...:.|.::.|:||.|..:|.:.:.:.|. .:|.|
plant   738 DEQKVCPCKDYENIVTFLTDLVRNMLKKMKSQPLLFVEILFSKTRKECHYINAEYM-LHELGHLR 801

  Fly   823 ------TKGAWTEE--------------------QESELRFLFEENQRNPETDKDVIDWILDNLV 861
                  .|.:.|||                    .|:::...:::..:|  .|.|:::
plant   802 KQMGNQEKFSGTEEFGTSSDKGWAHRSLADALGDDEADVVISYDQGFQN--EDDDMVE------- 857

  Fly   862 DKTRNRRTVLKKLKELGLLFKAPTKRSTKSAQSGKNVWQPEEDDELRSLYDQHRIEPDCLERLVN 926
            ||:                 ..|:||..:....|      :.|.:::.|||:::.:.:| .||:.
plant   858 DKS-----------------AGPSKRKRRLVLDG------DMDIKIKDLYDRYKDDKNC-SRLIA 898

  Fly   927 EFAERRSKQQIIKRMLQIHLIAD----KSEILPAKKGRGKDKPKKDVEMEGEGDEFDFAEEPMFE 987
            |                 :|:.|    .:::....|..|.:..|:  ...|..|..|..
plant   899 E-----------------NLVPDGGISAAQVTNKLKQLGLETRKR--LRRGGTDHLDAT------ 938

  Fly   988 DQGYKKPKSKPKKVQKRQMVRTPLDVGTIRALIGQVDSEKYQSAIEWLQECLQDASEDTEEAVED 1052
              ...:|.:..|:|......:..|    |:.|..:...||        :.|...|||...|
plant   939 --SLAQPSNTRKRVSSFSKEQETL----IKELYKKFKDEK--------RCCYLIASELGSE---- 985

  Fly  1053 DDGVPLLPLMENQKNAMEDGDFQKVLVALGMQPPISGMEAYWRIPIYLNSADLILRSKILAGEEV 1117
                          |........:.|..||::.| .|.:         :.|.::|:
plant   986 --------------NTYTTAQVSRKLKQLGLRLP-RGKK---------SEAGMMLK--------- 1017

  Fly  1118 DAEPEDEAADDEDGEEAEESDEEEDFLEKHSRQRKENIATQQQRKLDSLMFNQSDDETEQRAPPK 1182
                     ||.|...|:||::|.....|:.:.||.....||...::.:....|:|.||:.  ..
plant  1018 ---------DDHDDSSADESEDETLLAFKNRKSRKNQKNKQQTGSINEITPGGSEDNTERN--ET 1071

  Fly  1183 AKDKPKASEKKAKRKVKGKAKESKDCNDDGTDKAELEKPNTDDLFNQLRAKRATKIKLSDMALNE 1247
            :..:|.|.|              ::.||......|..:..||             :.:||.  ..
plant  1072 SLHEPTAGE--------------EEDNDQSYITRESRQSETD-------------VHISDN--GP 1107

  Fly  1248 STNAAQEADDDAFNFNSEDYRARLLELEDEEQNSKDADENGGDKENITNKSLQRARRVNVIDSDS 1312
            ||:..::.     |.:|::      ||||:|. :...|::.....::|...|.|.:...|:|.|.
plant  1108 STSLPEDP-----NLSSDN------ELEDDEL-ADWGDDSAAGGASLTQSPLSRRKLKMVLDKDD 1160

  Fly  1313 DND 1315
            ::|
plant  1161 EDD 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
timeout	NP_524341.3	TIMELESS	23..281	CDD:282651	70/284 (25%)
		TIMELESS_C	736..1217	CDD:252956	94/516 (18%)
ATIM	NP_001330129.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I4180
eggNOG	1	0.900	-	-		E1_KOG1974
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	127	1.000	Inparanoid score	I1918
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D839367at2759
OrthoFinder	1	1.000	-	-		FOG0004685
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102693
Panther	1	1.100	-	-	LDO	PTHR22940
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.870