Sequence 1: | NP_524340.2 | Gene: | sim / 41612 | FlyBaseID: | FBgn0004666 | Length: | 688 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_005060.1 | Gene: | SIM2 / 6493 | HGNCID: | 10883 | Length: | 667 | Species: | Homo sapiens |
Alignment Length: | 546 | Identity: | 280/546 - (51%) |
---|---|---|---|
Similarity: | 328/546 - (60%) | Gaps: | 95/546 - (17%) |
- Green bases have known domain annotations that are detailed below.
Fly 25 MKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWG 89
Fly 90 S-SPAMQRGATIKELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEYIHN 153
Fly 154 YDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCVLAK 218
Fly 219 RNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNMFMFR 283
Fly 284 AKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYRFLTK 348
Fly 349 GGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVKRE------------ 401
Fly 402 -------------------PISPAAQAAQAAQAAQAAQ---------AAQAAQAAHVAQAVQAQV 438
Fly 439 VVVPQQSVVV-----------------QPQCAGATGQPVGPGTPVSLA---LSASPKLDP----Y 479
Fly 480 FEPELP--LQPAVT-PVPPTNNSSSS 502 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
sim | NP_524340.2 | HLH | 26..78 | CDD:238036 | 46/51 (90%) |
PAS | 102..215 | CDD:279347 | 66/112 (59%) | ||
PAS | 102..163 | CDD:214512 | 53/60 (88%) | ||
PAS | 278..376 | CDD:238075 | 69/97 (71%) | ||
PAS_3 | 291..377 | CDD:285623 | 59/85 (69%) | ||
SIM2 | NP_005060.1 | HLH | 2..52 | CDD:238036 | 44/49 (90%) |
PAS | 79..>159 | CDD:279347 | 60/104 (58%) | ||
PAS | 88..>158 | CDD:238075 | 50/94 (53%) | ||
PAS | 229..328 | CDD:238075 | 69/98 (70%) | ||
PAS_3 | 243..329 | CDD:285623 | 59/85 (69%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 356..389 | 1/32 (3%) | |||
SIM_C | 359..660 | CDD:284122 | 28/163 (17%) | ||
Nuclear localization signal. /evidence=ECO:0000269|PubMed:14697214 | 367..386 | 0/18 (0%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 409..428 | 3/18 (17%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 500..520 | 7/20 (35%) | |||
DUF4712 | 578..>653 | CDD:292458 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 139 | 1.000 | Domainoid score | I4792 |
eggNOG | 1 | 0.900 | - | - | E1_KOG3558 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 474 | 1.000 | Inparanoid score | I1506 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000232 | |
OrthoInspector | 1 | 1.000 | - | - | otm42294 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_106200 | |
Panther | 1 | 1.100 | - | - | O | PTHR23043 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2563 |
SonicParanoid | 1 | 1.000 | - | - | X501 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
12 | 11.850 |