Protein Alignment sim and ss

DIOPT Version :10

• Sequence 1: NP_524340.2
• Gene: sim / 41612
• FlyBaseID: FBgn0004666
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001163629.2
• Gene: ss / 41988
• FlyBaseID: FBgn0003513
• Length: 1015
• Species: Drosophila melanogaster
• Alignment Length: 832
• Identity: 180/832 - (21%)
• Similarity: 310/832 - (37%)
• Gaps: 220/832 - (26%)

  Fly    31 NAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGL---GEAWGSSP 92
            |.::..||:.|.|...||.|||....|.|:||:.|::||:.|||:.:..|...:   .|..|..|
  Fly    32 NPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLP 96

  Fly    93 AMQR--GATIKELGSH---------LLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNS 146
            .:..  |...:|||:.         .||.|:||:.::..:|::.:.:.:...:||..|.::...|
  Fly    97 HIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQS 161

  Fly   147 IFEYIHNYDQDEMNAIL----SLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKT 207
            ::|.:|:.|::|:...|    .|...::...||:|..|                  ...:.:|::
  Fly   162 VYELVHSEDREELQRQLLWNSFLPADMSSMQLAETLAP------------------DKALYLERS 208

  Fly   208 FFLRMKCVLAKRNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLP--SSAI 270
            |.:|.:|:|.      .||||..:...|.:|..      .||....:...|....:..|  ..::
  Fly   209 FTVRFRCLLD------NTSGFLRLDIRGRIKVL------HGQNRKTEEPPLALFAYCTPFGPPSL 261

  Fly   271 TEIKLHQNMFMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYK 335
            .||...:|||..:.|||..|:..|.|...:.||...:|:....|..:|..|:..:..:||.||..
  Fly   262 LEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMGGYDLVHYDDLAYVASAHQELLKT 326

  Fly   336 GQVTTKYYRFLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLV--------LNE 392
            |......||:..|.|.|.|:|:.:.||:  ::|:..|::..:..|.:.|..||:        ::.
  Fly   327 GASGMIAYRYQKKDGEWQWLQTSSRLVY--KNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSY 389

  Fly   393 IQTGVVKR----------------------EPISP----------------AAQAAQAAQAAQAA 419
            :.||:...                      .|::|                ..::.:..|.....
  Fly   390 LDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQP 454

  Fly   420 QAAQAA----QAAHVAQAVQAQVVVVPQQSV-----------VVQPQCAGATGQPVGPGTPVSLA 469
            |..|.:    |....|.||..:.:..|..:|           ...|..:.|....:|...|.:..
  Fly   455 QTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAF 519

  Fly   470 LSASPKLDPYFEPELPLQPAV----TPVPPTNNSSSSSNNNNGVWHHHHV------QQQQQSG-- 522
            ...|..|...:.    ||.||    |..|.:...:|:...|..:.:..:.      ::.|::|
  Fly   520 YPVSENLFHQYR----LQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKY 580

  Fly   523 ----SMDHDSLSYTQLYPPLN---------DLVVSSS---SSVGGGTASSAG--------GGSSA 563
                |..:.|.:.|....||.         :::..||   |.|||.|.:..|        .|::|
  Fly   581 YSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTA 645

  Fly   564 SAS------------------SSGV------YSTEMQYP-----DTTTGN-LYY---NNNNHYYY 595
            :|:                  ||||      ..|....|     .|..|| |.|   ||||:
  Fly   646 AAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNN--- 707

  Fly   596 DYDATVDVAT---------------SMIRP------------FSANSNSCSSSSESERQLSTGNA 633
                .::.||               |...|            :||:|::.|...:.::||.....
  Fly   708 ----DLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQR 768

  Fly   634 SIVNETSPSQTTYSDLSHNFELSYFSDNSSQQHQHQQQQQHLMEQQHLQYQY 685
            .:.:..|...::.:....:.:..:.|....||.|.|||..|.....|..:.:
  Fly   769 GVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHH 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sim	NP_524340.2	bHLH-PAS_dSIM_like	25..86	CDD:381583	21/57 (37%)
		PAS	102..215	CDD:395786	26/125 (21%)
		PAS_3	291..377	CDD:430001	24/85 (28%)
ss	NP_001163629.2	bHLH-PAS_spineless_like	24..87	CDD:381573	21/54 (39%)
		PAS	123..178	CDD:214512	14/54 (26%)
		PAS_3	282..366	CDD:430001	24/85 (28%)