| Sequence 1: | NP_524340.2 | Gene: | sim / 41612 | FlyBaseID: | FBgn0004666 | Length: | 688 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_835740.2 | Gene: | sim1a / 260351 | ZFINID: | ZDB-GENE-020829-1 | Length: | 745 | Species: | Danio rerio |
| Alignment Length: | 796 | Identity: | 325/796 - (40%) |
|---|---|---|---|
| Similarity: | 398/796 - (50%) | Gaps: | 211/796 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 25 MKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWG 89
Fly 90 SSPAMQRGATI----KELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEY 150
Fly 151 IHNYDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCV 215
Fly 216 LAKRNAGLTTSGFKVIHCSGYLKARIYP-DRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNM 279
Fly 280 FMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYR 344
Fly 345 FLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVK-----REPIS 404
Fly 405 PAAQAAQAAQAAQAAQAAQAAQAAHVAQAVQAQVVVVPQQSVVVQPQCAGATGQ--PVGPGTPVS 467
Fly 468 LALSASPKL-------------DPYFEPE-----LPL---------------------------- 486
Fly 487 ------QP----------AVTPVPPTNNSSSSSNNNNGVWHH-HHVQQQQQSGSMDHDSLSYTQL 534
Fly 535 YPPLNDLVVSSSSSVGGGTASSAGGGSSASASSSG----------VYSTEMQY------------ 577
Fly 578 -------PDTTTGNLYYNNNNHYYYDYDATVDVA----TSMIRPFSANSNSCSSSSESERQLSTG 631
Fly 632 NASIVNETSPSQ--------------------------------TTYSDLSHNFELSYFSDNS-- 662
Fly 663 SQQHQHQQQQQHLMEQ 678 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sim | NP_524340.2 | HLH | 26..78 | CDD:238036 | 47/51 (92%) |
| PAS | 102..215 | CDD:279347 | 66/112 (59%) | ||
| PAS | 102..163 | CDD:214512 | 54/60 (90%) | ||
| PAS | 278..376 | CDD:238075 | 73/97 (75%) | ||
| PAS_3 | 291..377 | CDD:285623 | 62/85 (73%) | ||
| sim1a | NP_835740.2 | HLH | 2..52 | CDD:238036 | 45/49 (92%) |
| PAS | 79..>141 | CDD:279347 | 54/61 (89%) | ||
| PAS | 88..>158 | CDD:238075 | 50/94 (53%) | ||
| PAS | 229..328 | CDD:238075 | 73/98 (74%) | ||
| PAS_3 | 243..329 | CDD:285623 | 62/85 (73%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 350..413 | 11/79 (14%) | |||
| SIM_C | 359..647 | CDD:284122 | 52/326 (16%) | ||
| Nuclear localization signal. /evidence=ECO:0000250 | 368..387 | 1/32 (3%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 140 | 1.000 | Domainoid score | I4708 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3558 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 469 | 1.000 | Inparanoid score | I1488 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000232 | |
| OrthoInspector | 1 | 1.000 | - | - | otm24682 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_106200 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23043 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2563 |
| SonicParanoid | 1 | 1.000 | - | - | X501 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.850 | |||||