Protein Alignment pic and ddb1

DIOPT Version :10

• Sequence 1: NP_650257.1
• Gene: pic / 41611
• FlyBaseID: FBgn0260962
• Length: 1140
• Species: Drosophila melanogaster
• Sequence 2: NP_956920.2
• Gene: ddb1 / 393599
• ZFINID: ZDB-GENE-040426-1272
• Length: 1140
• Species: Danio rerio
• Alignment Length: 1147
• Identity: 696/1147 - (60%)
• Similarity: 870/1147 - (75%)
• Gaps: 14/1147 - (1%)

  Fly     1 MSHHYVVTAQKPTAVVACLTGNFTSPTDLNLIIARNNQVEIDLVTPEGLRPLKEININGTIAVMR 65
            ||::|||||||||||.||:||:|||..||||:||:|.::||..||.|||||:||:.:.|.||||.
Zfish     1 MSYNYVVTAQKPTAVNACITGHFTSAEDLNLLIAKNTRLEIYAVTAEGLRPVKEVGMYGKIAVME 65

  Fly    66 HFRPPDSNKDLLFILTRRYNVMILEARMVNDVITVVTKANGNVSDSVGIPSEGGVIAAIDPKARV 130
            .|||...:||||||||.:||..|||.:...|.|.::|:|:|||.|.:|.|||.|:|..:||:.|:
Zfish    66 LFRPKGESKDLLFILTAKYNACILEYKQSGDSIDIITRAHGNVQDRIGRPSETGIIGIVDPECRM 130

  Fly   131 IGMCLYQGLFTIIPMDKDASELKATNLRMDELNVYDVEFLHGCLNPTVIVIHKDSDGRHVKSHEI 195
            ||:.||.|||.:||:|::..||||.|:|::||.|.||:||:||..|||..|::|..|||||::|:
Zfish   131 IGLRLYDGLFKVIPLDRENRELKAFNIRLEELQVIDVQFLYGCQAPTVCFIYQDPQGRHVKTYEV 195

  Fly   196 NLRDKEFMKIAWKQDNVETEATMLIPVPSPIGGVIVIGRESIVYHDGSNYHAVAPLTFRQSTINC 260
            :||:|||.|..|||:|||.||:|:||||.|.||.|:||:|||.||:|..|.||||...:||||.|
Zfish   196 SLREKEFNKGPWKQENVEAEASMVIPVPEPFGGAIIIGQESITYHNGDKYLAVAPPIIKQSTIVC 260

  Fly   261 YARVSSNGLRYLLGNMDGQLYMLFLGTAETSKG-VTVKDIKVEQLGEISIPECITYLDNGFLYIG 324
            :.||..||.|||||:|:|:|:||.|...|...| |.:||:.||.|||.||.||:||||||.:::|
Zfish   261 HNRVDPNGSRYLLGDMEGRLFMLLLEKEELMDGAVVLKDLHVELLGETSIAECLTYLDNGVVFVG 325

  Fly   325 ARHGDSQLVRLNSEAID-GSYVVPVENFTNLAPILDIAVVDLDRQGQGQIITCSGSFKDGSLRII 388
            :|.||||||:||.::.| ||||..:|.||||.||:|:.||||:||||||::||||:||:||||||
Zfish   326 SRLGDSQLVKLNVDSNDQGSYVGVMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRII 390

  Fly   389 RIGIGIQEHACIDLPGIKGMWSLKVGVDES--PYENTLVLAFVGHTRILTLSGEEVEETEIPGFA 451
            |.||||.|||.||||||||:|.|:   .||  ..::.|||:|||.||:|.||||||||||:.||.
Zfish   391 RNGIGIHEHASIDLPGIKGLWPLR---SESSRDTDDMLVLSFVGQTRVLMLSGEEVEETELQGFV 452

  Fly   452 SDLQTFLCSNVDYDQLIQVTSDSVRLVSSATKALVAEWRPTGDRTIGVVSCNTTQILVASACDIF 516
            .:.|||.|.||.:.||||:||.|||||:..:||||:||:....|.|.|.|||.||:::|....::
Zfish   453 DNQQTFFCGNVAHQQLIQITSVSVRLVTQDSKALVSEWKEPQGRNISVASCNNTQVVLAVGRVLY 517

  Fly   517 YIVIEDGSLREQSRRTLAYEVACLDITPLDETQKKSDLVAVGLWTDISAVILSLPDLETIYTEKL 581
            |:.|..|.|::.|...:.:||||||||||.|....|.:.||||||||||.:|.||....::.|.|
Zfish   518 YLQILSGELKQISSTEMEHEVACLDITPLGERTADSCICAVGLWTDISARLLKLPCFTPLHKEML 582

  Fly   582 SGEIIPRSILMTTFEGIHYLLCALGDGSMYYFIMDQTTGQLTDKKKVTLGTQPTTLRTFRSLSTT 646
            .|||||||||||||||.||||||||||:::||.:|..||.|:::||||||||||.|||||||||:
Zfish   583 GGEIIPRSILMTTFEGSHYLLCALGDGALFYFGLDIQTGVLSERKKVTLGTQPTVLRTFRSLSTS 647

  Fly   647 NVFACSDRPTVIYSSNHKLVFSNVNLKEVNHMCSLNAQAYPDSLALANKNAVILGTIDEIQKLHI 711
            ||||||||||||||||||||||||||||||:||.||::.|||||||||.:.:.:|||||||||||
Zfish   648 NVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSEGYPDSLALANNSTLTIGTIDEIQKLHI 712

  Fly   712 RTVPLGEGPRRIAYQESSQTFAVSTLRIDVHGRGG-AKPLRNSASTQAQNITCSSNFL-PKPGGG 774
            |||||.|.|:||.|||.||.|.|.:.|:::....| ...:|.||||||.:.:.||:.| |.....
Zfish   713 RTVPLYESPKRICYQEVSQCFGVLSSRVEMQDASGTTAAVRPSASTQALSSSVSSSKLFPSSTSP 777

  Fly   775 NSTAANAEVGQEIDVHNLLVIDQNTFEVLHAHQFVAPETISSLMSAKLGDDPNTYYVVATSLVIP 839
            :.|:    .|:|::||:|||:||:||||||||||:..|...|::|.|||.||..|::|.|::|.|
Zfish   778 HETS----FGEEVEVHSLLVVDQHTFEVLHAHQFLQNEYALSMVSCKLGRDPAVYFIVGTAMVYP 838

  Fly   840 EEPEPKVGRIIIFHYHENKLTQVAETKVDGTCYALVEFNGKVLAGIGSFVRLYEWTNEKELRMEC 904
            ||.|||.||||:|||.:.||..|||.:|.|..|::||||||:||.|.|.|||||||.|||||.||
Zfish   839 EEAEPKQGRIIVFHYTDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTAEKELRTEC 903

  Fly   905 NIQNMIAALFLKAKGDFILVGDLMRSITLLQHKQMEGIFVEIARDCEPKWMRAVEILDDDTFLGS 969
            |..|.|.||:||.|||||||||||||:.||.:|.|||.|.|||||..|.||.||||||||.|||:
Zfish   904 NHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGSFEEIARDFNPNWMSAVEILDDDNFLGA 968

  Fly   970 ETNGNLFVCQKDSAATTDEERQLLPELARFHLGDTVNVFRHGSLVMQNVGERTTPINGCVLYGTC 1034
            |...||||||||||||||||||.|.|:..||||:.||||.|||||:||:||.:||..|.||:||.
Zfish   969 ENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFSHGSLVLQNLGESSTPTQGSVLFGTV 1033

  Fly  1035 NGAIGIVTQIPQDFYDFLHGLEERLKKIIKSVGKIEHTYYRNFQINSKVEPSEGFIDGDLIESFL 1099
            ||.||:||.:.:.:|..|..|:.||.|:|||||||||:::|:|....|.|.:.||||||||||||
Zfish  1034 NGMIGLVTSLSEGWYSLLLDLQNRLNKVIKSVGKIEHSFWRSFHTERKTEQATGFIDGDLIESFL 1098

  Fly  1100 DLSRDKMRDAVQGLEL-TLNGERKSADVEDVIKIVEDLTRMH 1140
            ||.|.||::.|..|:: ..:|.::.|.|::||||||:|||:|
Zfish  1099 DLGRAKMQEVVSTLQIDDGSGMKREATVDEVIKIVEELTRIH 1140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pic	NP_650257.1	MMS1_N	75..542	CDD:463091	269/470 (57%)
		CPSF_A	790..1100	CDD:427182	200/309 (65%)
ddb1	NP_956920.2	None