Protein Alignment pic and ddb1

DIOPT Version :10

• Sequence 1: NP_650257.1
• Gene: pic / 41611
• FlyBaseID: FBgn0260962
• Length: 1140
• Species: Drosophila melanogaster
• Sequence 2: XP_002937687.4
• Gene: ddb1 / 100485735
• XenbaseID: XB-GENE-967908
• Length: 1140
• Species: Xenopus tropicalis
• Alignment Length: 1146
• Identity: 693/1146 - (60%)
• Similarity: 879/1146 - (76%)
• Gaps: 12/1146 - (1%)

  Fly     1 MSHHYVVTAQKPTAVVACLTGNFTSPTDLNLIIARNNQVEIDLVTPEGLRPLKEININGTIAVMR 65
            ||::|||||||||||.||:||:|||..||||:||:|.::||.:||||||||:||:.:.|.||||.
 Frog     1 MSYNYVVTAQKPTAVNACVTGHFTSEDDLNLLIAKNTRLEIYVVTPEGLRPVKEVGMYGKIAVME 65

  Fly    66 HFRPPDSNKDLLFILTRRYNVMILEARMVNDVITVVTKANGNVSDSVGIPSEGGVIAAIDPKARV 130
            .|||...:||||||||.:||..|||.:...|.|.::|:|:|||.|.:|.|||.|:|..|||..|:
 Frog    66 LFRPKGESKDLLFILTAKYNACILEYKQNGDSIDIITRAHGNVQDRIGRPSETGIIGIIDPDCRM 130

  Fly   131 IGMCLYQGLFTIIPMDKDASELKATNLRMDELNVYDVEFLHGCLNPTVIVIHKDSDGRHVKSHEI 195
            ||:.||.|||.:||:::|..||||.|:|::||:|.||:||:.|..||:..:::|..|||||::|:
 Frog   131 IGLRLYDGLFKVIPLERDNKELKAFNIRLEELHVIDVKFLYSCQAPTICFVYQDPQGRHVKTYEV 195

  Fly   196 NLRDKEFMKIAWKQDNVETEATMLIPVPSPIGGVIVIGRESIVYHDGSNYHAVAPLTFRQSTINC 260
            :||:|||.|..|||:|||.||:|:|.||.|.||.|:||:|||.||:|..|.|:||...:||||.|
 Frog   196 SLREKEFSKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVC 260

  Fly   261 YARVSSNGLRYLLGNMDGQLYMLFLGTAETSKG-VTVKDIKVEQLGEISIPECITYLDNGFLYIG 324
            :.||..||.|||||:|:|:|:||.|...|...| ||:||::||.|||.||.||:||||||.:::|
 Frog   261 HNRVDVNGSRYLLGDMEGRLFMLLLEKEEQMDGSVTLKDLRVELLGETSIAECLTYLDNGVVFVG 325

  Fly   325 ARHGDSQLVRLNSEAID-GSYVVPVENFTNLAPILDIAVVDLDRQGQGQIITCSGSFKDGSLRII 388
            :|.||||||:|.:|:.: |||||.:|.||||.||:|:.||||:||||||::||||:||:||||||
 Frog   326 SRLGDSQLVKLTAESNEQGSYVVVMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRII 390

  Fly   389 RIGIGIQEHACIDLPGIKGMWSLKVGVDESPYENTLVLAFVGHTRILTLSGEEVEETEIPGFASD 453
            |.||||.|||.||||||||:|.|:|..|... ::||||:|||.||:|||:|||||||::.||..|
 Frog   391 RNGIGIHEHASIDLPGIKGLWPLRVAADRDT-DDTLVLSFVGQTRVLTLTGEEVEETDLAGFVDD 454

  Fly   454 LQTFLCSNVDYDQLIQVTSDSVRLVSSATKALVAEWRPTGDRTIGVVSCNTTQILVASACDIFYI 518
            .|||.|.||.:.||||:||.|||||:...::||:||:....|.:.|.|||:.|:|:|....::|:
 Frog   455 QQTFFCGNVAHQQLIQITSASVRLVAQNPQSLVSEWKEPQGRKVSVCSCNSRQVLLAVGRVLYYL 519

  Fly   519 VIEDGSLREQSRRTLAYEVACLDITPLDETQKKSDLVAVGLWTDISAVILSLPDLETIYTEKLSG 583
            .|..|.||:.|...:.:||||||:|||..:...|.|.|:||||||||.|||||..:.::.|.|.|
 Frog   520 EIHPGELRQISCTEMEHEVACLDVTPLGGSDTLSSLCAIGLWTDISARILSLPGFQLLHKEMLGG 584

  Fly   584 EIIPRSILMTTFEGIHYLLCALGDGSMYYFIMDQTTGQLTDKKKVTLGTQPTTLRTFRSLSTTNV 648
            ||||||||||:||..||||||||||:::||.::..||.|:|:||||||||||.||||||||||||
 Frog   585 EIIPRSILMTSFESSHYLLCALGDGALFYFSLNTDTGLLSDRKKVTLGTQPTVLRTFRSLSTTNV 649

  Fly   649 FACSDRPTVIYSSNHKLVFSNVNLKEVNHMCSLNAQAYPDSLALANKNAVILGTIDEIQKLHIRT 713
            ||||||||||||||||||||||||||||:||.||::.|||||||||.:.:.:|||||||||||||
 Frog   650 FACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSEGYPDSLALANNSTLTIGTIDEIQKLHIRT 714

  Fly   714 VPLGEGPRRIAYQESSQTFAVSTLRIDVH-GRGGAKPLRNSASTQA--QNITCSSNFLPKPGGGN 775
            |||.|.||:|.|||.||.|.|.:.||:|. ..||:.|||.||||||  .:::||..|     .|:
 Frog   715 VPLYESPRKICYQEVSQCFGVLSSRIEVQDASGGSSPLRPSASTQALSSSVSCSKLF-----SGS 774

  Fly   776 STAANAEVGQEIDVHNLLVIDQNTFEVLHAHQFVAPETISSLMSAKLGDDPNTYYVVATSLVIPE 840
            ::......|:|::|||||:|||:||||||.|||:..|...||:|.|||.||.||:||.|::|.|:
 Frog   775 TSPHETSFGEEVEVHNLLIIDQHTFEVLHTHQFLQNEYTLSLVSCKLGKDPTTYFVVGTAMVYPD 839

  Fly   841 EPEPKVGRIIIFHYHENKLTQVAETKVDGTCYALVEFNGKVLAGIGSFVRLYEWTNEKELRMECN 905
            |.|||.|||::|.|::.||..|||.:|.|..|::||||||:||.|.|.|||||||.|||||.|||
 Frog   840 EAEPKQGRIVVFQYNDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTAEKELRTECN 904

  Fly   906 IQNMIAALFLKAKGDFILVGDLMRSITLLQHKQMEGIFVEIARDCEPKWMRAVEILDDDTFLGSE 970
            ..|.|.||:||.|||||||||||||:.||.:|.|||.|.|||||..|.||.||||||||.|||:|
 Frog   905 HYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAE 969

  Fly   971 TNGNLFVCQKDSAATTDEERQLLPELARFHLGDTVNVFRHGSLVMQNVGERTTPINGCVLYGTCN 1035
            ...||||||||||||||||||.|.|:..||||:.||||.||||||||:||.:.|..|.||:||.|
 Frog   970 NAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSPPTQGSVLFGTVN 1034

  Fly  1036 GAIGIVTQIPQDFYDFLHGLEERLKKIIKSVGKIEHTYYRNFQINSKVEPSEGFIDGDLIESFLD 1100
            |.||:||.:.:.:|:.|..::.||.|:|||||||||:::|:|....|.||:.|||||||||||||
 Frog  1035 GMIGLVTSLSESWYNLLLDVQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLD 1099

  Fly  1101 LSRDKMRDAVQGLEL-TLNGERKSADVEDVIKIVEDLTRMH 1140
            :||.||::.:..|:: ..:|.::...|:|:||:||:|||:|
 Frog  1100 ISRPKMQEVIANLQIDDGSGMKRETTVDDLIKVVEELTRIH 1140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pic	NP_650257.1	MMS1_N	75..542	CDD:463091	265/468 (57%)
		CPSF_A	790..1100	CDD:427182	200/309 (65%)
ddb1	XP_002937687.4	MMS1_N	75..543	CDD:463091	265/468 (57%)
		CPSF_A	789..1099	CDD:427182	200/309 (65%)