DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7966 and Selenbp1

DIOPT Version :9

Sequence 1:	NP_650256.2	Gene:	CG7966 / 41610	FlyBaseID:	FBgn0038115	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_543168.1	Gene:	Selenbp1 / 140927	RGDID:	620571	Length:	472	Species:	Rattus norvegicus

Alignment Length:	484	Identity:	243/484 - (50%)
Similarity:	336/484 - (69%)	Gaps:	14/484 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSNKTCCRGPGYATPLDAMRSGPREKLLYTVTVQPNLDEPHGDYLSTVDVDPESPTYCQIVHRTF 65
            |:.|....||||||||:||: ||||:::|...:..|......|||:||||||:||.|.|::||..
  Rat     1 MATKCTKCGPGYATPLEAMK-GPREEIVYLPCIYRNTGIEAPDYLATVDVDPKSPHYSQVIHRLP 64

  Fly    66 TNRKGDELHHSGWNACSSCYYVDESSKTVPKRDRLVLPSLNSDFIYILDVVTDPRKPEIVKTID- 129
            .....|||||||||.||||:  .:|:|:   ||:|:|||:.|..||::||.::||.|::.|.|:
  Rat    65 MPHLKDELHHSGWNTCSSCF--GDSTKS---RDKLILPSIISSRIYVVDVGSEPRAPKLHKVIEP 124

  Fly   130 GDVLKSHNVTAPHTTHCLANGNIMISVMGDAEGYAKGDFILFDSD-FNCIGTWTKGDKKALCGYD 193
            .::....|:...||:||||:|.:|||.:||.:|..||.|:|.|.: |...|||.|...:|..|||
  Rat   125 NEIHAKCNLGNLHTSHCLASGEVMISSLGDPQGNGKGGFVLLDGETFEVKGTWEKPGGEAPMGYD 189

  Fly   194 FWYQPYFDVMVSSEWGAPNKWRRGWKNVDLEDMSQYGCRLNFYKWSTQTLYQTIDLGSDGITPLE 258
            |||||..::|||:||.|||.::.|:....:| ...||..::.:.|....:.||:.: .||:.|||
  Rat   190 FWYQPRHNIMVSTEWAAPNVFKDGFNPAHVE-AGLYGSHIHVWDWQRHEIIQTLQM-KDGLIPLE 252

  Fly   259 IRFLHNPKKAEGFVGCALNAKVFHFKKKSDSDEFEAKKVIDIPGKLVDTGSGVAEDMGGMISDII 323
            |||||:|...:|||||||::.:..| .|::...:..:|||.:|.|.|.  ..:..:|.|:|:||:
  Rat   253 IRFLHDPDATQGFVGCALSSNIQRF-YKNEGGTWSVEKVIQVPSKKVK--GWMLPEMPGLITDIL 314

  Fly   324 ISLDDRFLYVNCWRHGDVRQYDITDPENPKLTGQLFLGGAICSDLPNVIVKEDKELKERPPARYV 388
            :||||||||.:.|.|||:|||||::|:.|:||||:||||:|... .:|.|.||:||..:|....|
  Rat   315 LSLDDRFLYFSNWLHGDIRQYDISNPKKPRLTGQIFLGGSIVKG-GSVQVLEDQELTCQPEPLVV 378

  Fly   389 KGRRLEGGPQMLQLSLDGKRLYVSSSLYSPWDKQFYPKMVSQGGHIVLIDVDTVNGGISLNEDFL 453
            ||:|:.|||||:|||||||||||::||||.|||||||.::.:|..::.|||||.|||:.||.:||
  Rat   379 KGKRVPGGPQMIQLSLDGKRLYVTTSLYSAWDKQFYPNLIREGSVMLQIDVDTANGGLKLNPNFL 443

  Fly   454 VDFANEPYGPSLPHEMRYPGGDCTSDIWL 482
            |||..||.||:|.||:|||||||:||||:
  Rat   444 VDFGKEPLGPALAHELRYPGGDCSSDIWI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7966	NP_650256.2	SBP56	6..482	CDD:283374	240/477 (50%)
CG7966	NP_650256.2	LVIVD repeat	321..358	CDD:293789	24/36 (67%)
Selenbp1	NP_543168.1	SBP56	7..472	CDD:283374	240/476 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346726
Domainoid	1	1.000	484	1.000	Domainoid score	I381
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2930
Inparanoid	1	1.050	487	1.000	Inparanoid score	I1380
OMA	1	1.010	-	-		QHG61143
OrthoDB	1	1.010	-	-		D227621at33208
OrthoFinder	1	1.000	-	-		FOG0003227
OrthoInspector	1	1.000	-	-		oto95692
orthoMCL	1	0.900	-	-		OOG6_104861
Panther	1	1.100	-	-	LDO	PTHR23300
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2649
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910