Protein Alignment Hsc70-2 and hscA

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 596
• Identity: 226/596 - (37%)
• Similarity: 335/596 - (56%)
• Gaps: 40/596 - (6%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |.|||||||.|.|...::.:.|.:|:.:|....||.|.:.:....:|..|:...|::..||:...
E. coli    21 AAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSV 85

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVY 134
            |||:||...|  ||:.....|::. .:|.|.|.||.    ......|..:|:.:|..:...|...
E. coli    86 KRLMGRSLAD--IQQRYPHLPYQFQASENGLPMIET----AAGLLNPVRVSADILKALAARATEA 144

  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199
            |.|::...|:||||||:|:|||.||||..:|||:|||::|||||||:|||||...:|.  :.::|
E. coli   145 LAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGV--IAVYD 207

  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264
            |||||||:|:|.:..| :|||.||.||:.|||:|||:.|.::..|:.....:||    .|..|.|
E. coli   208 LGGGTFDISILRLSRG-VFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSD----NRVQREL 267

  Fly   265 RTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDK 329
            ..|...||..||.:...::.:      ..:..:|||.:|.||...|.:.|:....|||.||.::.
E. coli   268 LDAAIAAKIALSDADSVTVNV------AGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEA 326

  Fly   330 KAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLL 394
            ..:.:||:||||||:|.:::.:.:.||...|. ||:||:.||.|||:||.||  ||:....::||
E. coli   327 DEVLEVVMVGGSTRVPLVRERVGEFFGRPPLT-SIDPDKVVAIGAAIQADIL--VGNKPDSEMLL 388

  Fly   395 VDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGT 459
            :||.|||||:||.||::..::.||..||..:.|.|||:.|.|.|::|.|.:|||.:.:|...|..
E. coli   389 LDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLAR 453

  Fly   460 FNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAE 524
            |.|.|||..|.|...|.|.|.::|||:|:|.|.:.|||....|.:....| |:.:||..|:.::.
E. coli   454 FALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYG-LTDSEIASMIKDSM 517

  Fly   525 KYKVEDDRQR----ERVQSKNNLE----------AYIYAC-RQAVDDAPSGVLSETERSKVRDKC 574
            .|..:|.:.|    ::|::...||          |.:.|. ||.:||| :..|||..:....|..
E. coli   518 SYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDA-AAHLSEVAQGDDVDAI 581

  Fly   575 SSEASWLDKNS 585
            ......:||.:
E. coli   582 EQAIKNVDKQT 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	226/596 (38%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	226/596 (38%)