Protein Alignment Hsc70-2 and SSA4

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_011029.3
• Gene: SSA4 / 856840
• SGDID: S000000905
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 640
• Identity: 424/640 - (66%)
• Similarity: 508/640 - (79%)
• Gaps: 14/640 - (2%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |:|||||||||||..:.|.:|||||||||||||||||||.:|||||||.||||.|||..||||||
Yeast     4 AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDA 68

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||||||.::..|.|.:|||||::.|||.::||:|||.|.|.|||||||:||||:|.||.:|
Yeast    69 KRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFL 133

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.:||||||||||||||||||||||||:|||||||||||||||||:||||||..:.|.|||||||
Yeast   134 GTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDL 198

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|||||| :||||||||||||||||||:||||..|||||||:|.|:..|.|:|||||
Yeast   199 GGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLR 262

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            ||.||||||||||.:.|:|||:|.||||||:.|:|||||||..||||||::|||:.|:|:|:||.
Yeast   263 TAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKS 327

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .|.::|||||||||||:|||:.|.|.||:.|.|||||||||||||||||||||..||..|||||:
Yeast   328 QIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLL 392

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            ||||||||||||||:||.|:.||:.||.|:.::|:||:|||..|.|||:||||..||||||||.|
Yeast   393 DVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKF 457

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            .|:||||||||||||||.||::|:|||||:|.:..||||.||||:||||||||.:||:|::||||
Yeast   458 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEK 522

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKNSLAEK 589
            :|.||:::.:|||:||.||:|.:..:.:|.:.. ...:.|.:..|:........:|||.:..|..
Yeast   523 FKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAAST 587

  Fly   590 EEFESHLKECQRICTPIMSKIHGGKKGKSSMG------------KGSHPTVEEVD 632
            ||::...||.:.:..|||||.:|...|....|            ..:.|||||||
Yeast   588 EEYKERQKELEGVANPIMSKFYGAAGGAPGAGPVPGAGAGPTGAPDNGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	422/638 (66%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	285/375 (76%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	422/638 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720