Protein Alignment Hsc70-2 and SSZ1

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 163/557 - (29%)
• Similarity: 276/557 - (49%)
• Gaps: 85/557 - (15%)

  Fly     5 PAIGIDLGTTYSCVGVWQNSK--VEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTV 67
            |.|||..|.|.|.: .:.|.|  |::|||..|.|..||.:::...:...|..|..|:..|.|||:
Yeast     4 PVIGITFGNTSSSI-AYINPKNDVDVIANPDGERAIPSALSYVGEDEYHGGQALQQLIRNPKNTI 67

  Fly    68 FDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFK---------GERKRFAPEEISSMV 123
            .:.:..||..||...:.        |..|  |.|.:||:.|         |:.::...:|:.|..
Yeast    68 INFRDFIGLPFDKCDVS--------KCAN--GAPAVEVDGKVGFVISRGEGKEEKLTVDEVVSRH 122

  Fly   124 LTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN 188
            |.:::..||.|:|..||:||:|||..|::.|:.|.|.:.:..||.:::.||||:||.||:.....
Yeast   123 LNRLKLAAEDYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHAEQFP 187

  Fly   189 LKGERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSD 253
            .:.:.||::.|.||...|.:|:::..| :|.:.|||.|..|||::.|..||.:||.||::|::::
Yeast   188 FEKDVNVVVADFGGIRSDAAVIAVRNG-IFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQAN 251

  Fly   254 IKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPV 318
            .:.|||:|.:|:......|:|||::|.|::.||:|.:|.|:::.|:|.|:|.:...:|......|
Yeast   252 PRKNARSLAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFV 316

  Fly   319 ERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQ-------DLFGGKQLNLSINPDEAVAYGAAV 376
            :..::.|::|...|..|:|.||.:..||:...|:       ::.|.:..|.|.||:|..|.|||:
Yeast   317 DSVIAKAELDPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAAL 381

  Fly   377 QAAILTGVGSSQIQDLL---LVDVAPLS--LGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQ 436
            ||.:::...:.::.:.|   :|:...|.  :|:..|.|....::......|.:::   .|....:
Yeast   382 QARLISDYDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKK---LTLKQAK 443

  Fly   437 NAVTIQVYEGE--------RAMTKDNNL-----------------------------LGTFNLTG 464
            ....|.||||:        ..:.|:.|.                             ||..|..|
Yeast   444 GDFLIGVYEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMELGIKNANG 508

  Fly   465 IPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEK 501
                      :|:.|::|.||.|.|.|:|..||.:.|
Yeast   509 ----------VEIIFNINKDGALRVTARDLKTGNAVK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	163/557 (29%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	132/393 (34%)